ENSGALG00000015645


Gallus gallus

Features
Gene ID: ENSGALG00000015645
  
Biological name :GRK4
  
Synonyms : G protein-coupled receptor kinase 4 / GRK4
  
Possible biological names infered from orthology : O70291 / P32298
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 82790891
Gene end: 82821245
  
Corresponding Affymetrix probe sets: GgaAffx.9971.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000025180
NCBI entrez gene - 422879     See in Manteia.
RefSeq - NM_001006459
RefSeq Peptide - NP_001006459
swissprot - Q5ZKL2
Ensembl - ENSGALG00000015645
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 grk4ENSDARG00000070448Danio rerio
 GRK4ENSG00000125388Homo sapiens
 Grk4ENSMUSG00000052783Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GRK5 / G protein-coupled receptor kinase 5 / P34947* / Q8VEB1*ENSGALG0000000940370
GRK6 / G protein-coupled receptor kinase 6 / O70293* / P43250*ENSGALG0000001405469
GRK7 / G protein-coupled receptor kinase 7 / Q8WTQ7*ENSGALG0000000280038
GRK3 / G protein-coupled receptor kinase 3 / P35626* / Q3UYH7* / Beta-adrenergic receptor kinase 2 *ENSGALG0000003709736


Protein motifs (from Interpro)
Interpro ID Name
 IPR000239  GPCR kinase
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR016137  RGS domain
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0031623 receptor internalization IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004703 G-protein coupled receptor kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Inactivation, recovery and regulation of the phototransduction cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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