ENSGALG00000037097


Gallus gallus

Features
Gene ID: ENSGALG00000037097
  
Biological name :GRK3
  
Synonyms : G protein-coupled receptor kinase 3 / GRK3
  
Possible biological names infered from orthology : Beta-adrenergic receptor kinase 2 / P35626 / Q3UYH7
  
Species: Gallus gallus
  
Chr. number: 15
Strand: 1
Band:
Gene start: 7052925
Gene end: 7093489
  
Corresponding Affymetrix probe sets: Gga.6318.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000054677
NCBI entrez gene - 416904     See in Manteia.
RefSeq - XM_015275493
RefSeq - XM_015275494
swissprot - A0A1D5PP79
Ensembl - ENSGALG00000037097
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 grk3ENSDARG00000104094Danio rerio
 GRK3ENSG00000100077Homo sapiens
 Grk3ENSMUSG00000042249Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GRK5 / G protein-coupled receptor kinase 5 / P34947* / Q8VEB1*ENSGALG0000000940331
GRK4 / G protein-coupled receptor kinase 4 / O70291* / P32298*ENSGALG0000001564530
GRK6 / G protein-coupled receptor kinase 6 / O70293* / P43250*ENSGALG0000001405430
GRK7 / G protein-coupled receptor kinase 7 / Q8WTQ7*ENSGALG0000000280023


Protein motifs (from Interpro)
Interpro ID Name
 IPR000239  GPCR kinase
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR001849  Pleckstrin homology domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011993  PH-like domain superfamily
 IPR016137  RGS domain
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0031623 receptor internalization IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004703 G-protein coupled receptor kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events
Cargo recognition for clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000019026 OXT* / AVP* / P35454* / P01185* / P35455* / P01178* / oxytocin* / arginine vasopressin* / oxytocin/neurophysin I prepropeptide*  / reaction






 

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