ENSGALG00000016323


Gallus gallus

Features
Gene ID: ENSGALG00000016323
  
Biological name :PDK3
  
Synonyms : PDK3 / pyruvate dehydrogenase kinase 3
  
Possible biological names infered from orthology : pyruvate dehydrogenase kinase, isoenzyme 3 / Q15120 / Q922H2
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 118089639
Gene end: 118139548
  
Corresponding Affymetrix probe sets: GgaAffx.10450.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051442
Ensembl peptide - ENSGALP00000026284
NCBI entrez gene - 418595     See in Manteia.
RefSeq - XM_015302359
RefSeq - NM_001006259
RefSeq Peptide - NP_001006259
swissprot - Q5ZLT2
swissprot - A0A1D5PF79
Ensembl - ENSGALG00000016323
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pdk3aENSDARG00000014527Danio rerio
 pdk3bENSDARG00000099791Danio rerio
 PDK3ENSG00000067992Homo sapiens
 Pdk3ENSMUSG00000035232Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PDK1 / pyruvate dehydrogenase kinase 1 / Q15118* / Q8BFP9* / [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial *ENSGALG0000001323569
PDK4 / pyruvate dehydrogenase kinase 4 / O70571* / Q16654* / pyruvate dehydrogenase kinase, isoenzyme 4*ENSGALG0000000970064
PDK2* / Q15119* / Q9JK42* / pyruvate dehydrogenase kinase 2* / [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial *ENSGALG0000004584661


Protein motifs (from Interpro)
Interpro ID Name
 IPR003594  Histidine kinase/HSP90-like ATPase
 IPR005467  Histidine kinase domain
 IPR018955  Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate IEA
 biological_processGO:0010906 regulation of glucose metabolic process IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IEA
 biological_processGO:0035357 peroxisome proliferator activated receptor signaling pathway IEA
 biological_processGO:0071398 cellular response to fatty acid IEA
 biological_processGO:0097411 hypoxia-inducible factor-1alpha signaling pathway IEA
 biological_processGO:2000377 regulation of reactive oxygen species metabolic process IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Regulation of pyruvate dehydrogenase (PDH) complex
Signaling by Retinoic Acid


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000016430 PDHA1 / PDHA2* / P35486* / P35487* / P08559* / P29803* / pyruvate dehydrogenase E1 alpha 1* / pyruvate dehydrogenase E1 alpha 1 subunit* / pyruvate dehydrogenase E1 alpha 2 subunit* / Pyruv...  / reaction
 ENSGALG00000007931 DLD / dihydrolipoamide dehydrogenase / O08749* / P09622* / Dihydrolipoyl dehydrogenase, mitochondrial *  / reaction
 ENSGALG00000007904 DLAT / dihydrolipoamide S-acetyltransferase / P10515* / Q8BMF4* / Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial *  / reaction
 ENSGALG00000029576 PDHB / pyruvate dehydrogenase E1 component subunit beta, mitochondrial / P11177* / Q9D051* / pyruvate dehydrogenase E1 beta subunit*  / reaction






 

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