ENSGALG00000009700


Gallus gallus

Features
Gene ID: ENSGALG00000009700
  
Biological name :PDK4
  
Synonyms : PDK4 / pyruvate dehydrogenase kinase 4
  
Possible biological names infered from orthology : O70571 / pyruvate dehydrogenase kinase, isoenzyme 4 / Q16654
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 23933443
Gene end: 23942823
  
Corresponding Affymetrix probe sets: Gga.16444.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000015774
NCBI entrez gene - 420570     See in Manteia.
RefSeq - NM_001199909
RefSeq Peptide - NP_001186838
swissprot - F1NYN2
Ensembl - ENSGALG00000009700
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pdk4ENSDARG00000054848Danio rerio
 PDK4ENSG00000004799Homo sapiens
 Pdk4ENSMUSG00000019577Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PDK1 / pyruvate dehydrogenase kinase 1 / Q15118* / Q8BFP9* / [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial *ENSGALG0000001323564
PDK3 / pyruvate dehydrogenase kinase 3 / Q15120* / Q922H2* / pyruvate dehydrogenase kinase, isoenzyme 3*ENSGALG0000001632362
PDK2* / Q15119* / Q9JK42* / pyruvate dehydrogenase kinase 2* / [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial *ENSGALG0000004584658


Protein motifs (from Interpro)
Interpro ID Name
 IPR003594  Histidine kinase/HSP90-like ATPase
 IPR005467  Histidine kinase domain
 IPR018955  Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006885 regulation of pH IEA
 biological_processGO:0008286 insulin receptor signaling pathway IEA
 biological_processGO:0009267 cellular response to starvation IEA
 biological_processGO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate IEA
 biological_processGO:0010565 regulation of cellular ketone metabolic process IEA
 biological_processGO:0010906 regulation of glucose metabolic process IEA
 biological_processGO:0042304 regulation of fatty acid biosynthetic process IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0042594 response to starvation IEA
 biological_processGO:0045124 regulation of bone resorption IEA
 biological_processGO:0046320 regulation of fatty acid oxidation IEA
 biological_processGO:0071398 cellular response to fatty acid IEA
 biological_processGO:0072593 reactive oxygen species metabolic process IEA
 biological_processGO:2000811 negative regulation of anoikis IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Regulation of pyruvate dehydrogenase (PDH) complex
Signaling by Retinoic Acid


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007931 DLD / dihydrolipoamide dehydrogenase / O08749* / P09622* / Dihydrolipoyl dehydrogenase, mitochondrial *  / reaction
 ENSGALG00000016430 PDHA1 / PDHA2* / P35486* / P35487* / P08559* / P29803* / pyruvate dehydrogenase E1 alpha 1* / pyruvate dehydrogenase E1 alpha 1 subunit* / pyruvate dehydrogenase E1 alpha 2 subunit* / Pyruv...  / reaction
 ENSGALG00000029576 PDHB / pyruvate dehydrogenase E1 component subunit beta, mitochondrial / P11177* / Q9D051* / pyruvate dehydrogenase E1 beta subunit*  / reaction
 ENSGALG00000007904 DLAT / dihydrolipoamide S-acetyltransferase / P10515* / Q8BMF4* / Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial *  / reaction






 

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