Manteia

ENSGALG00000029576

Gallus gallus

Features

Gene ID:	ENSGALG00000029576

Biological name :	PDHB

Synonyms :	PDHB / pyruvate dehydrogenase E1 component subunit beta, mitochondrial

Possible biological names infered from orthology :	P11177 / pyruvate dehydrogenase E1 beta subunit / Q9D051

Species:	Gallus gallus

Chr. number:	12
Strand:	-1
Band:
Gene start:	11850139
Gene end:	11854726

Corresponding Affymetrix probe sets:	Gga.9380.1.S1_at (Chicken Array) Gga.9380.2.S1_at (Chicken Array) Gga.9380.3.S1_a_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000046632 Ensembl peptide - ENSGALP00000046786 NCBI entrez gene - 416066 See in Manteia. RefSeq - NM_001198620 RefSeq - XM_015293107 RefSeq - XM_015293108 RefSeq Peptide - NP_001185549 swissprot - A0A1D5P291 swissprot - A0A1D5P1U2 Ensembl - ENSGALG00000029576

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
BCKDHB / 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial precursor / P21953* / Q6P3A8* / branched chain keto acid dehydrogenase E1 subunit beta* / 2-oxoisovalerate dehydrogenase...	ENSGALG00000040702	31

Protein motifs (from Interpro)

Interpro ID	Name
IPR005475	Transketolase-like, pyrimidine-binding domain
IPR009014	Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II
IPR027110	Pyruvate dehydrogenase E1 component subunit beta
IPR029061	Thiamin diphosphate-binding fold
IPR033247	Transketolase family
IPR033248	Transketolase, C-terminal domain

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006086	acetyl-CoA biosynthetic process from pyruvate	IEA
biological_process	GO:0006099	tricarboxylic acid cycle	IEA
biological_process	GO:0008152	metabolic process	IEA
cellular_component	GO:0005654	nucleoplasm	IEA
cellular_component	GO:0005739	mitochondrion	IEA
cellular_component	GO:0045254	pyruvate dehydrogenase complex	IEA
molecular_function	GO:0003824	catalytic activity	IEA
molecular_function	GO:0004738	pyruvate dehydrogenase activity	IEA
molecular_function	GO:0034604	pyruvate dehydrogenase (NAD+) activity	IEA

Pathways (from Reactome)

Pathway description

Regulation of pyruvate dehydrogenase (PDH) complex

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSGALG00000007904	DLAT / dihydrolipoamide S-acetyltransferase / P10515* / Q8BMF4* / Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial *	/ complex
ENSGALG00000016430	PDHA1 / PDHA2* / P35486* / P35487* / P08559* / P29803* / pyruvate dehydrogenase E1 alpha 1* / pyruvate dehydrogenase E1 alpha 1 subunit* / pyruvate dehydrogenase E1 alpha 2 subunit* / Pyruv...	/ complex
ENSGALG00000009700	PDK4 / pyruvate dehydrogenase kinase 4 / O70571* / Q16654* / pyruvate dehydrogenase kinase, isoenzyme 4*	/ reaction
ENSGALG00000016323	PDK3 / pyruvate dehydrogenase kinase 3 / Q15120* / Q922H2* / pyruvate dehydrogenase kinase, isoenzyme 3*	/ reaction
ENSGALG00000013235	PDK1 / pyruvate dehydrogenase kinase 1 / Q15118* / Q8BFP9* / [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial *	/ reaction
ENSGALG00000029576	PDHB / pyruvate dehydrogenase E1 component subunit beta, mitochondrial / P11177* / Q9D051* / pyruvate dehydrogenase E1 beta subunit*	/ complex
ENSGALG00000007931	DLD / dihydrolipoamide dehydrogenase / O08749* / P09622* / Dihydrolipoyl dehydrogenase, mitochondrial *	/ complex

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr