ENSGALG00000032247


Gallus gallus

Features
Gene ID: ENSGALG00000032247
  
Biological name :ATP1A1
  
Synonyms : ATP1A1 / sodium/potassium-transporting ATPase subunit alpha-1 precursor
  
Possible biological names infered from orthology : ATPase Na+/K+ transporting subunit alpha 1 / P05023 / Q8VDN2 / Sodium/potassium-transporting ATPase subunit alpha-1
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 80243655
Gene end: 80267671
  
Corresponding Affymetrix probe sets: Gga.2155.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046142
Ensembl peptide - ENSGALP00000056482
Ensembl peptide - ENSGALP00000051049
NCBI entrez gene - 396530     See in Manteia.
RefSeq - NM_205521
RefSeq Peptide - NP_990852
swissprot - A0A1D5PU80
swissprot - A0A1D5PE50
swissprot - A0A1D5P0G4
Ensembl - ENSGALG00000032247
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atp1a1a.1ENSDARG00000002791Danio rerio
 atp1a1a.2ENSDARG00000007739Danio rerio
 atp1a1a.3ENSDARG00000039131Danio rerio
 atp1a1a.4ENSDARG00000001870Danio rerio
 atp1a1a.5ENSDARG00000040252Danio rerio
 atp1a1bENSDARG00000019856Danio rerio
 ATP1A1ENSG00000163399Homo sapiens
 Atp1a1ENSMUSG00000033161Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ATP12A / potassium-transporting ATPase alpha chain 2 / P54707* / Q9Z1W8* / ATPase H+/K+ transporting non-gastric alpha2 subunit*ENSGALG0000000646965
ATP2A3 / sarcoplasmic/endoplasmic reticulum calcium ATPase 3 / Q64518* / Q93084* / ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3*ENSGALG0000000156428
ATP2A2 / sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform 1 / O55143* / P16615* / Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 * / ATPase sarcoplasmic/endoplasmic reticul...ENSGALG0000003228727
ATP2C1 / ATPase secretory pathway Ca2+ transporting 1 / P98194* / Q80XR2* / Calcium-transporting ATPase type 2C member 1 *ENSGALG0000003434027
ATP2C2 / ATPase secretory pathway Ca2+ transporting 2 / A7L9Z8* / O75185* / Calcium-transporting ATPase type 2C member 2 *ENSGALG0000003574326


Protein motifs (from Interpro)
Interpro ID Name
 IPR001757  P-type ATPase
 IPR004014  Cation-transporting P-type ATPase, N-terminal
 IPR005775  P-type ATPase subfamily IIC, subunit alpha
 IPR006068  Cation-transporting P-type ATPase, C-terminal
 IPR008250  P-type ATPase, A domain superfamily
 IPR018303  P-type ATPase, phosphorylation site
 IPR023214  HAD superfamily
 IPR023298  P-type ATPase, transmembrane domain superfamily
 IPR023299  P-type ATPase, cytoplasmic domain N


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002026 regulation of the force of heart contraction IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0006883 cellular sodium ion homeostasis IEA
 biological_processGO:0008217 regulation of blood pressure IEA
 biological_processGO:0010107 potassium ion import IEA
 biological_processGO:0010248 establishment or maintenance of transmembrane electrochemical gradient IEA
 biological_processGO:0030007 cellular potassium ion homeostasis IEA
 biological_processGO:0031947 negative regulation of glucocorticoid biosynthetic process IEA
 biological_processGO:0036376 sodium ion export across plasma membrane IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0045822 negative regulation of heart contraction IEA
 biological_processGO:0045823 positive regulation of heart contraction IEA
 biological_processGO:0045989 positive regulation of striated muscle contraction IEA
 biological_processGO:0071383 cellular response to steroid hormone stimulus IEA
 biological_processGO:0086009 membrane repolarization IEA
 biological_processGO:1903416 response to glycoside IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005890 sodium:potassium-exchanging ATPase complex IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030315 T-tubule IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0042383 sarcolemma IEA
 cellular_componentGO:0043209 myelin sheath IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005391 sodium:potassium-exchanging ATPase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051087 chaperone binding IEA
 molecular_functionGO:1990239 steroid hormone binding IEA


Pathways (from Reactome)
Pathway description
Ion homeostasis
Ion transport by P-type ATPases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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