ENSGALG00000032287


Gallus gallus

Features
Gene ID: ENSGALG00000032287
  
Biological name :ATP2A2
  
Synonyms : ATP2A2 / sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform 1
  
Possible biological names infered from orthology : ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 / O55143 / P16615 / Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
  
Species: Gallus gallus
  
Chr. number: 15
Strand: -1
Band:
Gene start: 5344147
Gene end: 5385167
  
Corresponding Affymetrix probe sets: Gga.2151.1.S1_at (Chicken Array)   Gga.5828.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000054240
Ensembl peptide - ENSGALP00000061438
Ensembl peptide - ENSGALP00000059190
Ensembl peptide - ENSGALP00000054653
NCBI entrez gene - 396446     See in Manteia.
RefSeq - NM_001271973
RefSeq - NM_001271974
RefSeq Peptide - NP_001258903
RefSeq Peptide - NP_001258902
swissprot - A0A1D5PP56
swissprot - A0A1L1RKB7
swissprot - A0A1L1RRK7
swissprot - A0A1D5PN02
Ensembl - ENSGALG00000032287
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atp2a2aENSDARG00000029439Danio rerio
 atp2a2aENSDARG00000005122Danio rerio
 ATP2A2ENSG00000174437Homo sapiens
 Atp2a2ENSMUSG00000029467Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ATP2A3 / sarcoplasmic/endoplasmic reticulum calcium ATPase 3 / Q64518* / Q93084* / ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3*ENSGALG0000000156478
ATP2C1 / ATPase secretory pathway Ca2+ transporting 1 / P98194* / Q80XR2* / Calcium-transporting ATPase type 2C member 1 *ENSGALG0000003434032
ATP2C2 / ATPase secretory pathway Ca2+ transporting 2 / A7L9Z8* / O75185* / Calcium-transporting ATPase type 2C member 2 *ENSGALG0000003574329
ATP12A / potassium-transporting ATPase alpha chain 2 / P54707* / Q9Z1W8* / ATPase H+/K+ transporting non-gastric alpha2 subunit*ENSGALG0000000646927
ATP1A1 / sodium/potassium-transporting ATPase subunit alpha-1 precursor / P05023* / Q8VDN2* / ATPase Na+/K+ transporting subunit alpha 1* / Sodium/potassium-transporting ATPase subunit alpha-1 *ENSGALG0000003224727


Protein motifs (from Interpro)
Interpro ID Name
 IPR001757  P-type ATPase
 IPR004014  Cation-transporting P-type ATPase, N-terminal
 IPR005782  P-type ATPase, subfamily IIA, SERCA-type
 IPR006068  Cation-transporting P-type ATPase, C-terminal
 IPR008250  P-type ATPase, A domain superfamily
 IPR018303  P-type ATPase, phosphorylation site
 IPR023214  HAD superfamily
 IPR023298  P-type ATPase, transmembrane domain superfamily
 IPR023299  P-type ATPase, cytoplasmic domain N


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002026 regulation of the force of heart contraction IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006874 cellular calcium ion homeostasis IEA
 biological_processGO:0006984 ER-nucleus signaling pathway IEA
 biological_processGO:0006996 organelle organization IEA
 biological_processGO:0014883 transition between fast and slow fiber IEA
 biological_processGO:0014898 cardiac muscle hypertrophy in response to stress IEA
 biological_processGO:0032469 endoplasmic reticulum calcium ion homeostasis IEA
 biological_processGO:0032470 positive regulation of endoplasmic reticulum calcium ion concentration IEA
 biological_processGO:0033292 T-tubule organization IEA
 biological_processGO:0034599 cellular response to oxidative stress IEA
 biological_processGO:0045822 negative regulation of heart contraction IEA
 biological_processGO:0070296 sarcoplasmic reticulum calcium ion transport IEA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:0099132 ATP hydrolysis coupled cation transmembrane transport IEA
 biological_processGO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter IEA
 biological_processGO:1903515 calcium ion transport from cytosol to endoplasmic reticulum IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016529 sarcoplasmic reticulum IEA
 cellular_componentGO:0097470 ribbon synapse IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005388 calcium-transporting ATPase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0044548 S100 protein binding IEA


Pathways (from Reactome)
Pathway description
Reduction of cytosolic Ca++ levels
Ion homeostasis
Ion transport by P-type ATPases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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