ENSGALG00000034434


Gallus gallus

Features
Gene ID: ENSGALG00000034434
  
Biological name :IDH2
  
Synonyms : IDH2 / isocitrate dehydrogenase
  
Possible biological names infered from orthology : isocitrate dehydrogenase (NADP(+)) 2, mitochondrial / Isocitrate dehydrogenase [NADP], mitochondrial / P48735 / P54071
  
Species: Gallus gallus
  
Chr. number: 10
Strand: -1
Band:
Gene start: 20053601
Gene end: 20056916
  
Corresponding Affymetrix probe sets: Gga.7268.2.S1_s_at (Chicken Array)   GgaAffx.11955.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049035
NCBI entrez gene - 431056     See in Manteia.
RefSeq - NM_001031599
RefSeq - XM_015292125
RefSeq Peptide - NP_001026770
swissprot - A0A1D5P8I7
Ensembl - ENSGALG00000034434
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 idh2ENSDARG00000003795Danio rerio
 IDH2ENSG00000182054Homo sapiens
 Idh2ENSMUSG00000030541Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IDH1 / isocitrate dehydrogenase (NADP(+)) 1, cytosolic / O75874* / O88844* / Isocitrate dehydrogenase [NADP] cytoplasmic *ENSGALG0000000881863


Protein motifs (from Interpro)
Interpro ID Name
 IPR004790  Isocitrate dehydrogenase NADP-dependent
 IPR019818  Isocitrate/isopropylmalate dehydrogenase, conserved site
 IPR024084  Isopropylmalate dehydrogenase-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006099 tricarboxylic acid cycle IEA
 biological_processGO:0006102 isocitrate metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004448 isocitrate dehydrogenase activity IEA
 molecular_functionGO:0004450 isocitrate dehydrogenase (NADP+) activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051287 NAD binding IEA


Pathways (from Reactome)
Pathway description
Transcriptional activation of mitochondrial biogenesis
Citric acid cycle (TCA cycle)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000032496 SIRT3 / sirtuin 3 / Q8R104* / Q9NTG7*  / reaction
 ENSGALG00000034434 IDH2 / isocitrate dehydrogenase / P54071* / P48735* / Isocitrate dehydrogenase [NADP], mitochondrial * / isocitrate dehydrogenase (NADP(+)) 2, mitochondrial*  / complex






 

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