ENSGALG00000037787


Gallus gallus

Features
Gene ID: ENSGALG00000037787
  
Biological name :MEF2D
  
Synonyms : MEF2D / myocyte enhancer factor 2D
  
Possible biological names infered from orthology : Myocyte-specific enhancer factor 2D / Q14814 / Q63943
  
Species: Gallus gallus
  
Chr. number: 25
Strand: -1
Band:
Gene start: 1557867
Gene end: 1620174
  
Corresponding Affymetrix probe sets: Gga.4344.1.S1_at (Chicken Array)   Gga.4344.1.S1_s_at (Chicken Array)   Gga.4344.2.S1_s_at (Chicken Array)   GgaAffx.11787.1.S1_at (Chicken Array)   GgaAffx.11787.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045472
Ensembl peptide - ENSGALP00000060363
Ensembl peptide - ENSGALP00000058572
Ensembl peptide - ENSGALP00000053437
Ensembl peptide - ENSGALP00000050527
NCBI entrez gene - 431059     See in Manteia.
RefSeq - NM_001031600
RefSeq Peptide - NP_001026771
swissprot - A0A1L1RNL2
swissprot - A0A1D5Q003
swissprot - A0A1D5PCN7
swissprot - A0A1D5NYL4
Ensembl - ENSGALG00000037787
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mef2dENSDARG00000040237Danio rerio
 MEF2DENSG00000116604Homo sapiens
 Mef2dENSMUSG00000001419Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MEF2A / myocyte enhancer factor 2A / Q02078* / Q60929* / Mus musculus myocyte enhancer factor 2A (Mef2a), transcript variant 7, mRNA.*ENSGALG0000003236654
MEF2C / myocyte enhancer factor 2C / Q06413* / Q8CFN5* / Mus musculus myocyte enhancer factor 2C (Mef2c), transcript variant 14, mRNA.*ENSGALG0000001464547
MEF2B* / Q02080* / BORCS8-MEF2B* / BORCS8-MEF2B readthrough* / myocyte enhancer factor 2B*ENSGALG0000003755819


Protein motifs (from Interpro)
Interpro ID Name
 IPR002100  Transcription factor, MADS-box
 IPR011989  Armadillo-like helical
 IPR014710  RmlC-like jelly roll fold
 IPR022102  Holliday junction regulator protein family C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001649 osteoblast differentiation IEA
 biological_processGO:0001958 endochondral ossification IEA
 biological_processGO:0002062 chondrocyte differentiation IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007512 adult heart development IEA
 biological_processGO:0035914 skeletal muscle cell differentiation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:1904707 positive regulation of vascular smooth muscle cell proliferation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0033613 activating transcription factor binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
CDO in myogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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