ENSDARG00000040237


Danio rerio

Features
Gene ID: ENSDARG00000040237
  
Biological name :mef2d
  
Synonyms : mef2d / myocyte enhancer factor 2d
  
Possible biological names infered from orthology : Myocyte-specific enhancer factor 2D / Q14814 / Q63943
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 29072874
Gene end: 29194517
  
Corresponding Affymetrix probe sets: Dr.1403.1.S1_at (Zebrafish Array)   Dr.25090.1.A1_at (Zebrafish Array)   Dr.7439.1.A1_at (Zebrafish Array)   NM_131317_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000027449
Ensembl peptide - ENSDARP00000123748
Ensembl peptide - ENSDARP00000139550
Ensembl peptide - ENSDARP00000046113
Ensembl peptide - ENSDARP00000115546
NCBI entrez gene - 30580     See in Manteia.
RefSeq - NM_131317
RefSeq Peptide - NP_571392
swissprot - F1Q910
swissprot - F1QE20
swissprot - F8W591
ZFIN ID - ZDB-GENE-990415-164
Ensembl - ENSDARG00000040237
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MEF2DENSGALG00000037787Gallus gallus
 MEF2DENSG00000116604Homo sapiens
 Mef2dENSMUSG00000001419Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mef2aa / myocyte enhancer factor 2aa / MEF2A* / Q60929* / Q02078* / myocyte enhancer factor 2A* / Mus musculus myocyte enhancer factor 2A (Mef2a), transcript variant 7, mRNA.*ENSDARG0000003175647
mef2cb / myocyte enhancer factor 2cb / MEF2C* / Q8CFN5* / Q06413* / myocyte enhancer factor 2C* / Mus musculus myocyte enhancer factor 2C (Mef2c), transcript variant 14, mRNA.*ENSDARG0000000941845
mef2ca / myocyte enhancer factor 2caENSDARG0000002976445
mef2ab / myocyte enhancer factor 2abENSDARG0000005752732
mef2b / myocyte enhancer factor 2b / Q02080* / BORCS8-MEF2B* / BORCS8-MEF2B readthrough*ENSDARG0000009317027


Protein motifs (from Interpro)
Interpro ID Name
 IPR002100  Transcription factor, MADS-box
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR022102  Holliday junction regulator protein family C-terminal
 IPR033896  MADS MEF2-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030241 skeletal muscle myosin thick filament assembly IGI
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0060914 heart formation IGI
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
CDO in myogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000114 heart heart aplastic , abnormal
Show

 ZFA:0000115 heart rudiment heart rudiment aplastic , abnormal
heart rudiment cardiac muscle cell disorganized , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved ventral , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel morphology , abnormal
intersegmental vessel decreased length , abnormal
Show

 ZFA:0009116 slow muscle cell slow muscle cell myofibril composition , abnormal
slow muscle cell immature , abnormal
Show

 ZFA:0009117 fast muscle cell fast muscle cell myofibril composition , abnormal
Show

 ZFA:0009316 cardiac muscle cell cardiac muscle cell undifferentiated , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr