ENSGALG00000038154


Gallus gallus

Features
Gene ID: ENSGALG00000038154
  
Biological name :YAP1
  
Synonyms : transcriptional coactivator YAP1 / YAP1
  
Possible biological names infered from orthology : P46937 / P46938 / Yes associated protein 1
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 182684536
Gene end: 182765393
  
Corresponding Affymetrix probe sets: Gga.19642.1.S1_at (Chicken Array)   Gga.3093.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045081
Ensembl peptide - ENSGALP00000053936
NCBI entrez gene - 396171     See in Manteia.
RefSeq - NM_205243
RefSeq Peptide - NP_990574
swissprot - A0A1D5PM63
swissprot - A0A1D5NXI5
Ensembl - ENSGALG00000038154
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 yap1ENSDARG00000068401Danio rerio
 YAP1ENSG00000137693Homo sapiens
 Yap1ENSMUSG00000053110Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
WWTR1 / WW domain containing transcription regulator 1 / Q9EPK5* / Q9GZV5*ENSGALG0000001041244


Protein motifs (from Interpro)
Interpro ID Name
 IPR001202  WW domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000902 cell morphogenesis IEA
 biological_processGO:0001570 vasculogenesis IEA
 biological_processGO:0003143 embryonic heart tube morphogenesis IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010837 regulation of keratinocyte proliferation IEA
 biological_processGO:0030216 keratinocyte differentiation IEA
 biological_processGO:0030857 negative regulation of epithelial cell differentiation IEA
 biological_processGO:0030903 notochord development IEA
 biological_processGO:0032570 response to progesterone IEA
 biological_processGO:0033148 positive regulation of intracellular estrogen receptor signaling pathway IEA
 biological_processGO:0035019 somatic stem cell population maintenance IEA
 biological_processGO:0035329 hippo signaling IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046622 positive regulation of organ growth IEA
 biological_processGO:0048339 paraxial mesoderm development IEA
 biological_processGO:0048368 lateral mesoderm development IEA
 biological_processGO:0050767 regulation of neurogenesis IEA
 biological_processGO:0050847 progesterone receptor signaling pathway IEA
 biological_processGO:0060242 contact inhibition IEA
 biological_processGO:0060449 bud elongation involved in lung branching IEA
 biological_processGO:0060487 lung epithelial cell differentiation IEA
 biological_processGO:0060828 regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0065003 protein-containing complex assembly IEA
 biological_processGO:0071300 cellular response to retinoic acid IEA
 biological_processGO:0071480 cellular response to gamma radiation IEA
 biological_processGO:0072091 regulation of stem cell proliferation IEA
 biological_processGO:0072307 regulation of metanephric nephron tubule epithelial cell differentiation IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 biological_processGO:1902459 positive regulation of stem cell population maintenance IEA
 biological_processGO:2000737 negative regulation of stem cell differentiation IEA
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0071148 TEAD-1-YAP complex IEA
 cellular_componentGO:0071149 TEAD-2-YAP complex IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001076 transcription factor activity, RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0033613 activating transcription factor binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0070064 proline-rich region binding IEA


Pathways (from Reactome)
Pathway description
Nuclear signaling by ERBB4
Signaling by Hippo
YAP1- and WWTR1 (TAZ)-stimulated gene expression
RUNX1 regulates transcription of genes involved in differentiation of HSCs
RUNX3 regulates YAP1-mediated transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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