ENSGALG00000038758


Gallus gallus

Features
Gene ID: ENSGALG00000038758
  
Biological name :MMP15
  
Synonyms : matrix metallopeptidase 15 / MMP15
  
Possible biological names infered from orthology : Matrix metalloproteinase-15 / O54732 / P51511
  
Species: Gallus gallus
  
Chr. number: 11
Strand: -1
Band:
Gene start: 489693
Gene end: 493137
  
Corresponding Affymetrix probe sets: Gga.17545.1.S1_at (Chicken Array)   Gga.18923.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000055346
NCBI entrez gene - 415629     See in Manteia.
RefSeq - XM_015292312
swissprot - A0A1D5PR25
Ensembl - ENSGALG00000038758
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mmp15aENSDARG00000051962Danio rerio
 mmp15bENSDARG00000013072Danio rerio
 MMP15ENSG00000102996Homo sapiens
 Mmp15ENSMUSG00000031790Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MMP16 / matrix metallopeptidase 16 / P51512* / Q9WTR0* / Matrix metalloproteinase-16 *ENSGALG0000003203152
MMP24 / matrix metallopeptidase 24 / Q9R0S2* / Q9Y5R2* / Matrix metalloproteinase-24 Processed matrix metalloproteinase-24*ENSGALG0000004109351
MMP27 / matrix metalloproteinase-27 precursor / Q9H306* / matrix metallopeptidase 27*ENSGALG0000001906027
MMP1* / MMP8* / Mmp1b* / Mmp1a* / P22894* / P03956* / O70138* / Neutrophil collagenase * / matrix metallopeptidase 1* / matrix metallopeptidase 8* / interstitial collagenase A preproprotein *ENSGALG0000001906127
MMP13 / collagenase 3 precursor / P45452* / P33435* / Collagenase 3 * / matrix metallopeptidase 13*ENSGALG0000001718327
MMP10ENSGALG0000001906326
MMP11 / matrix metallopeptidase 11 / P24347* / Q02853* / Stromelysin-3 *ENSGALG0000000596824
MMP3* / MMP10* / O55123* / P08254* / P09238* / matrix metallopeptidase 3* / matrix metallopeptidase 10*ENSGALG0000002629723
MMP7 / matrilysin precursor / P09237* / matrix metallopeptidase 7*ENSGALG0000001718417


Protein motifs (from Interpro)
Interpro ID Name
 IPR000585  Hemopexin-like domain
 IPR001818  Peptidase M10, metallopeptidase
 IPR002477  Peptidoglycan binding-like
 IPR006026  Peptidase, metallopeptidase
 IPR018486  Hemopexin, conserved site
 IPR018487  Hemopexin-like repeats
 IPR021158  Peptidase M10A, cysteine switch, zinc binding site
 IPR021190  Peptidase M10A
 IPR021805  Peptidase M10A, matrix metallopeptidase, C-terminal
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR028729  Matrix metalloproteinase-15


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0035987 endodermal cell differentiation IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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