ENSGALG00000032031


Gallus gallus

Features
Gene ID: ENSGALG00000032031
  
Biological name :MMP16
  
Synonyms : matrix metallopeptidase 16 / MMP16
  
Possible biological names infered from orthology : Matrix metalloproteinase-16 / P51512 / Q9WTR0
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 124196141
Gene end: 124391614
  
Corresponding Affymetrix probe sets: Gga.2098.1.S1_at (Chicken Array)   Gga.2098.2.S1_at (Chicken Array)   Gga.2098.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047828
Ensembl peptide - ENSGALP00000059786
Ensembl peptide - ENSGALP00000058286
Ensembl peptide - ENSGALP00000050576
NCBI entrez gene - 396116     See in Manteia.
RefSeq - NM_205197
RefSeq Peptide - NP_990528
swissprot - A0A1L1RLZ2
swissprot - A0A1D5PZ77
swissprot - A0A1D5PCT5
Ensembl - ENSGALG00000032031
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mmp16bENSDARG00000058876Danio rerio
 MMP16ENSG00000156103Homo sapiens
 Mmp16ENSMUSG00000028226Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MMP24 / matrix metallopeptidase 24 / Q9R0S2* / Q9Y5R2* / Matrix metalloproteinase-24 Processed matrix metalloproteinase-24*ENSGALG0000004109365
MMP15 / matrix metallopeptidase 15 / O54732* / P51511* / Matrix metalloproteinase-15 *ENSGALG0000003875855
MMP13 / collagenase 3 precursor / P45452* / P33435* / Collagenase 3 * / matrix metallopeptidase 13*ENSGALG0000001718329
MMP27 / matrix metalloproteinase-27 precursor / Q9H306* / matrix metallopeptidase 27*ENSGALG0000001906029
MMP1* / MMP8* / Mmp1b* / Mmp1a* / P22894* / P03956* / O70138* / Neutrophil collagenase * / matrix metallopeptidase 1* / matrix metallopeptidase 8* / interstitial collagenase A preproprotein *ENSGALG0000001906129
MMP10ENSGALG0000001906328
MMP11 / matrix metallopeptidase 11 / P24347* / Q02853* / Stromelysin-3 *ENSGALG0000000596825
MMP3* / MMP10* / O55123* / P08254* / P09238* / matrix metallopeptidase 3* / matrix metallopeptidase 10*ENSGALG0000002629725
MMP7 / matrilysin precursor / P09237* / matrix metallopeptidase 7*ENSGALG0000001718417


Protein motifs (from Interpro)
Interpro ID Name
 IPR000585  Hemopexin-like domain
 IPR001818  Peptidase M10, metallopeptidase
 IPR002477  Peptidoglycan binding-like
 IPR006026  Peptidase, metallopeptidase
 IPR018486  Hemopexin, conserved site
 IPR018487  Hemopexin-like repeats
 IPR021158  Peptidase M10A, cysteine switch, zinc binding site
 IPR021190  Peptidase M10A
 IPR021805  Peptidase M10A, matrix metallopeptidase, C-terminal
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR028697  Matrix metalloproteinase-16


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001503 ossification IEA
 biological_processGO:0001958 endochondral ossification IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0016485 protein processing IEA
 biological_processGO:0030574 collagen catabolic process IEA
 biological_processGO:0035988 chondrocyte proliferation IEA
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IEA
 biological_processGO:0060348 bone development IEA
 biological_processGO:0097094 craniofacial suture morphogenesis IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070006 metalloaminopeptidase activity IEA


Pathways (from Reactome)
Pathway description
Activation of Matrix Metalloproteinases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008341 FURIN / furin, paired basic amino acid cleaving enzyme / P09958* / P23188*  / reaction






 

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