ENSGALG00000019061


Gallus gallus

Features
Gene ID: ENSGALG00000019061
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology : interstitial collagenase A preproprotein / matrix metallopeptidase 1 / matrix metallopeptidase 8 / MMP1 / Mmp1a / Mmp1b / MMP8 / Neutrophil collagenase / O70138 / P03956 / P22894
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 182507123
Gene end: 182513346
  
Corresponding Affymetrix probe sets: GgaAffx.11018.1.S1_s_at (Chicken Array)   GgaAffx.25192.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000027716
NCBI entrez gene - 418982     See in Manteia.
RefSeq - XM_417176
swissprot - E1C9D9
Ensembl - ENSGALG00000019061
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MMP1ENSG00000196611Homo sapiens
 MMP8ENSG00000118113Homo sapiens
 Mmp1aENSMUSG00000043089Mus musculus
 Mmp1bENSMUSG00000041620Mus musculus
 Mmp8ENSMUSG00000005800Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MMP27 / matrix metalloproteinase-27 precursor / Q9H306* / matrix metallopeptidase 27*ENSGALG0000001906058
MMP10ENSGALG0000001906353
MMP13 / collagenase 3 precursor / P45452* / P33435* / Collagenase 3 * / matrix metallopeptidase 13*ENSGALG0000001718350
MMP3* / MMP10* / O55123* / P08254* / P09238* / matrix metallopeptidase 3* / matrix metallopeptidase 10*ENSGALG0000002629744
MMP24 / matrix metallopeptidase 24 / Q9R0S2* / Q9Y5R2* / Matrix metalloproteinase-24 Processed matrix metalloproteinase-24*ENSGALG0000004109339
MMP16 / matrix metallopeptidase 16 / P51512* / Q9WTR0* / Matrix metalloproteinase-16 *ENSGALG0000003203138
MMP15 / matrix metallopeptidase 15 / O54732* / P51511* / Matrix metalloproteinase-15 *ENSGALG0000003875838
MMP11 / matrix metallopeptidase 11 / P24347* / Q02853* / Stromelysin-3 *ENSGALG0000000596830
MMP7 / matrilysin precursor / P09237* / matrix metallopeptidase 7*ENSGALG0000001718429


Protein motifs (from Interpro)
Interpro ID Name
 IPR000585  Hemopexin-like domain
 IPR001818  Peptidase M10, metallopeptidase
 IPR002477  Peptidoglycan binding-like
 IPR006026  Peptidase, metallopeptidase
 IPR018486  Hemopexin, conserved site
 IPR018487  Hemopexin-like repeats
 IPR021158  Peptidase M10A, cysteine switch, zinc binding site
 IPR021190  Peptidase M10A
 IPR024079  Metallopeptidase, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Basigin interactions
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000037940 IGFBP3 / insulin like growth factor binding protein 3 / P17936* / P47878*  / reaction
 ENSGALG00000001328 BSG / P17790 / Basigin / P18572* / P35613* / basigin (Ok blood group)*  / reaction / complex
 ENSGALG00000035282 IGF2 / P33717 / Insulin-like growth factor II / P01344* / P09535* / insulin like growth factor 2* / Insulin-like growth factor II Insulin-like growth factor II Preptin*  / reaction
 ENSGALG00000012755 IGF-I / P18254 / Insulin-like growth factor I / IGF1* / P05017* / P05019* / insulin like growth factor 1*  / reaction
 ENSGALG00000003580 MMP2 / Q90611 / 72 kDa type IV collagenase / P08253* / P33434* / matrix metallopeptidase 2* / 72 kDa type IV collagenase PEX*  / reaction
 ENSGALG00000006992 MMP9 / matrix metalloproteinase-9 precursor / P14780* / P41245* / matrix metallopeptidase 9* / Matrix metalloproteinase-9 *  / reaction






 

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