ENSDARG00000058876


Danio rerio

Features
Gene ID: ENSDARG00000058876
  
Biological name :mmp16b
  
Synonyms : matrix metallopeptidase 16b (membrane-inserted) / mmp16b
  
Possible biological names infered from orthology : matrix metallopeptidase 16 / Matrix metalloproteinase-16 / MMP16 / P51512 / Q9WTR0
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 3630307
Gene end: 3678029
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000076272
Ensembl peptide - ENSDARP00000121807
NCBI entrez gene - 572034     See in Manteia.
RefSeq - XM_009296801
swissprot - F1Q608
swissprot - F1R8N4
ZFIN ID - ZDB-GENE-061009-22
Ensembl - ENSDARG00000058876
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MMP16ENSGALG00000032031Gallus gallus
 MMP16ENSG00000156103Homo sapiens
 Mmp16ENSMUSG00000028226Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mmp24 / matrix metallopeptidase 24 / Q9R0S2* / Q9Y5R2* / Matrix metalloproteinase-24 Processed matrix metalloproteinase-24*ENSDARG0000001889657
mmp15b / matrix metallopeptidase 15b / MMP15* / P51511* / matrix metallopeptidase 15*ENSDARG0000001307251
mmp15a / matrix metallopeptidase 15a / MMP15* / O54732* / P51511* / matrix metallopeptidase 15* / Matrix metalloproteinase-15 *ENSDARG0000005196247
mmp14b / matrix metallopeptidase 14b (membrane-inserted) / MMP14* / P50281* / P53690* / matrix metallopeptidase 14* / Matrix metalloproteinase-14 *ENSDARG0000000838846
mmp14a / matrix metallopeptidase 14a (membrane-inserted) / MMP14* / P50281* / P53690* / matrix metallopeptidase 14* / Matrix metalloproteinase-14 *ENSDARG0000000223545
mmp25b / matrix metallopeptidase 25b / MMP25* / Q9NPA2* / matrix metallopeptidase 25*ENSDARG0000001055630
mmp17a / matrix metallopeptidase 17a / MMP17* / Q9R0S3* / Q9ULZ9* / matrix metallopeptidase 17* / Matrix metalloproteinase-17 *ENSDARG0000007891529
mmp25a / matrix metallopeptidase 25a / MMP25* / Q3U435* / Q9NPA2* / matrix metallopeptidase 25* / Matrix metalloproteinase-25 *ENSDARG0000007729028
mmp11a / matrix metallopeptidase 11a / MMP11* / P24347* / Q02853* / Stromelysin-3 * / matrix metallopeptidase 11*ENSDARG0000002632526
mmp13a / matrix metallopeptidase 13aENSDARG0000011445126
mmp13a / matrix metallopeptidase 13aENSDARG0000001239526
mmp13b / matrix metallopeptidase 13b / MMP13* / P45452* / P33435* / Collagenase 3 * / matrix metallopeptidase 13*ENSDARG0000010079426
mmp11b / matrix metallopeptidase 11b / MMP11* / P24347* / Q02853* / Stromelysin-3 * / matrix metallopeptidase 11*ENSDARG0000001671826
mmp20a / matrix metallopeptidase 20a (enamelysin) / MMP20* / O60882* / P57748* / matrix metallopeptidase 20* / Matrix metalloproteinase-20 *ENSDARG0000008988725
mmp30 / matrix metallopeptidase 30 / MMP7* / P09237* / matrix metallopeptidase 7*ENSDARG0000004588724
mmp17b / matrix metallopeptidase 17bENSDARG0000010295624
LO018336.1ENSDARG0000010840124
mmp20b / matrix metallopeptidase 20b (enamelysin)ENSDARG0000005547923


Protein motifs (from Interpro)
Interpro ID Name
 IPR000585  Hemopexin-like domain
 IPR001818  Peptidase M10, metallopeptidase
 IPR002477  Peptidoglycan binding-like
 IPR006026  Peptidase, metallopeptidase
 IPR018486  Hemopexin, conserved site
 IPR018487  Hemopexin-like repeats
 IPR021158  Peptidase M10A, cysteine switch, zinc binding site
 IPR021190  Peptidase M10A
 IPR021805  Peptidase M10A, matrix metallopeptidase, C-terminal
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR033739  Peptidase M10A, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Activation of Matrix Metalloproteinases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000062909 furina / furin (paired basic amino acid cleaving enzyme) a / FURIN* / P09958* / furin, paired basic amino acid cleaving enzyme*  / reaction
 ENSDARG00000070971 furinb / furin (paired basic amino acid cleaving enzyme) b / FURIN* / P23188* / P09958* / furin, paired basic amino acid cleaving enzyme*  / reaction






 

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