ENSDARG00000077290


Danio rerio

Features
Gene ID: ENSDARG00000077290
  
Biological name :mmp25a
  
Synonyms : matrix metallopeptidase 25a / mmp25a
  
Possible biological names infered from orthology : matrix metallopeptidase 25 / Matrix metalloproteinase-25 / MMP25 / Q3U435 / Q9NPA2
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 32620575
Gene end: 32629489
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000126081
swissprot - I3IT28
ZFIN ID - ZDB-GENE-070820-22
Ensembl - ENSDARG00000077290
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MMP25ENSG00000008516Homo sapiens
 Mmp25ENSMUSG00000023903Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mmp25b / matrix metallopeptidase 25b / MMP25* / Q9NPA2* / matrix metallopeptidase 25*ENSDARG0000001055647
mmp17a / matrix metallopeptidase 17a / MMP17* / Q9R0S3* / Q9ULZ9* / matrix metallopeptidase 17* / Matrix metalloproteinase-17 *ENSDARG0000007891537
mmp15b / matrix metallopeptidase 15b / MMP15* / P51511* / matrix metallopeptidase 15*ENSDARG0000001307232
mmp24 / matrix metallopeptidase 24 / Q9R0S2* / Q9Y5R2* / Matrix metalloproteinase-24 Processed matrix metalloproteinase-24*ENSDARG0000001889632
mmp17b / matrix metallopeptidase 17bENSDARG0000010295631
mmp14b / matrix metallopeptidase 14b (membrane-inserted) / MMP14* / P50281* / P53690* / matrix metallopeptidase 14* / Matrix metalloproteinase-14 *ENSDARG0000000838831
mmp15a / matrix metallopeptidase 15a / MMP15* / O54732* / P51511* / matrix metallopeptidase 15* / Matrix metalloproteinase-15 *ENSDARG0000005196231
mmp16b / matrix metallopeptidase 16b (membrane-inserted) / MMP16* / P51512* / Q9WTR0* / matrix metallopeptidase 16* / Matrix metalloproteinase-16 *ENSDARG0000005887630
mmp14a / matrix metallopeptidase 14a (membrane-inserted) / MMP14* / P50281* / P53690* / matrix metallopeptidase 14* / Matrix metalloproteinase-14 *ENSDARG0000000223530
mmp11a / matrix metallopeptidase 11a / MMP11* / P24347* / Q02853* / Stromelysin-3 * / matrix metallopeptidase 11*ENSDARG0000002632526
LO018336.1ENSDARG0000010840126
mmp11b / matrix metallopeptidase 11b / MMP11* / P24347* / Q02853* / Stromelysin-3 * / matrix metallopeptidase 11*ENSDARG0000001671825
mmp20a / matrix metallopeptidase 20a (enamelysin) / MMP20* / O60882* / P57748* / matrix metallopeptidase 20* / Matrix metalloproteinase-20 *ENSDARG0000008988725
mmp13b / matrix metallopeptidase 13b / MMP13* / P45452* / P33435* / Collagenase 3 * / matrix metallopeptidase 13*ENSDARG0000010079424
mmp30 / matrix metallopeptidase 30 / MMP7* / P09237* / matrix metallopeptidase 7*ENSDARG0000004588724
mmp13a / matrix metallopeptidase 13aENSDARG0000011445124
mmp13a / matrix metallopeptidase 13aENSDARG0000001239524
mmp20b / matrix metallopeptidase 20b (enamelysin)ENSDARG0000005547922


Protein motifs (from Interpro)
Interpro ID Name
 IPR000585  Hemopexin-like domain
 IPR001818  Peptidase M10, metallopeptidase
 IPR002477  Peptidoglycan binding-like
 IPR006026  Peptidase, metallopeptidase
 IPR018487  Hemopexin-like repeats
 IPR021190  Peptidase M10A
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR028733  Matrix metalloproteinase-25
 IPR033739  Peptidase M10A, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006954 inflammatory response IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Activation of Matrix Metalloproteinases
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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