ENSGALG00000039139


Gallus gallus

Features
Gene ID: ENSGALG00000039139
  
Biological name :TNS3
  
Synonyms : tensin 3 / TNS3
  
Possible biological names infered from orthology : Q5SSZ5 / Q68CZ2
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 55221387
Gene end: 55442502
  
Corresponding Affymetrix probe sets: Gga.14180.1.S1_at (Chicken Array)   Gga.14180.1.S1_s_at (Chicken Array)   GgaAffx.23915.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050177
Ensembl peptide - ENSGALP00000061905
NCBI entrez gene - 420792     See in Manteia.
RefSeq - XM_015275855
RefSeq - XM_015275852
RefSeq - XM_015275853
RefSeq - XM_015275854
RefSeq - NM_001277761
RefSeq - XM_015275851
RefSeq Peptide - NP_001264690
swissprot - A0A1L1RSX2
swissprot - A0A1D5PBP7
Ensembl - ENSGALG00000039139
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tns3.2ENSDARG00000031911Danio rerio
 TNS3ENSG00000136205Homo sapiens
 Tns3ENSMUSG00000020422Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TNS1 / tensin / Q9HBL0* / tensin 1*ENSGALG0000004101345
DNAJC6 / DnaJ heat shock protein family (Hsp40) member C6 / O75061* / Q80TZ3*ENSGALG0000001104113
GAK / cyclin G associated kinase / O14976* / cyclin-G-associated kinase isoform 3 *ENSGALG0000001535212
TNS4 / tensin 4 / Q8BZ33* / Q8IZW8*ENSGALG0000002830812
PTEN / phosphatase and tensin homolog / O08586* / P60484*ENSGALG000000036348
TPTE* / TPTE2* / Q6XPS3* / P56180* / transmembrane phosphatase with tensin homology* / transmembrane phosphoinositide 3-phosphatase and tensin homolog 2*ENSGALG000000170315


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000980  SH2 domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily
 IPR013625  Tensin/EPS8 phosphotyrosine-binding domain
 IPR014020  Tensin phosphatase, C2 domain
 IPR029021  Protein-tyrosine phosphatase-like
 IPR029023  Tensin-type phosphatase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0048286 lung alveolus development IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005925 focal adhesion IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
MET interacts with TNS proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000036883 MET / hepatocyte growth factor receptor precursor / P08581* / MET proto-oncogene, receptor tyrosine kinase*  / complex / reaction
 ENSGALG00000033974 HGF / hepatocyte growth factor / P14210* / Q08048* / Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain*  / complex / reaction






 

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