ENSGALG00000040938


Gallus gallus

Features
Gene ID: ENSGALG00000040938
  
Biological name :NLGN1
  
Synonyms : neuroligin-1 / NLGN1
  
Possible biological names infered from orthology : Q8N2Q7 / Q99K10
  
Species: Gallus gallus
  
Chr. number: 9
Strand: -1
Band:
Gene start: 18812849
Gene end: 19083894
  
Corresponding Affymetrix probe sets: Gga.10094.1.S1_at (Chicken Array)   Gga.10094.1.S1_s_at (Chicken Array)   GgaAffx.20871.1.S1_at (Chicken Array)   GgaAffx.5773.1.S1_s_at (Chicken Array)   GgaAffx.5773.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046584
Ensembl peptide - ENSGALP00000061310
Ensembl peptide - ENSGALP00000060683
Ensembl peptide - ENSGALP00000054073
Ensembl peptide - ENSGALP00000053763
NCBI entrez gene - 424980     See in Manteia.
RefSeq - XM_015291660
RefSeq - XM_015291653
RefSeq - XM_015291654
RefSeq - XM_015291655
RefSeq - XM_015291656
RefSeq - XM_015291658
RefSeq - XM_015291659
RefSeq - NM_001081502
RefSeq - XM_015291652
RefSeq Peptide - NP_001074971
swissprot - D3WGL0
swissprot - D3WGK9
swissprot - D2X2H3
swissprot - A0A1D5PMJ4
swissprot - D3WGL1
Ensembl - ENSGALG00000040938
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nlgn1ENSDARG00000077710Danio rerio
 NLGN1ENSG00000169760Homo sapiens
 Nlgn1ENSMUSG00000063887Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NLGN4L / neuroligin-4, X-linked / Q8N0W4* / Q8NFZ3* / NLGN4X* / NLGN4Y* / neuroligin 4, Y-linked*ENSGALG0000001662871
NLGN3 / neuroligin 3 / Q8BYM5* / Q9NZ94*ENSGALG0000000555369
BCHE / cholinesterase precursor / P06276* / Q03311* / Cholinesterase * / butyrylcholinesterase*ENSGALG0000003486023
CEL / bile salt-activated lipase precursor / Q64285* / carboxyl ester lipase* / Bile salt-activated lipase *ENSGALG0000003443621
CES1* / Ces1h* / Ces1g* / Ces1f* / Ces1e* / Ces1d* / Ces1c* / Ces1b* / Ces1a* / CES4A* / Q91WU0* / P23141* / P23953* / Q5XG92* / Q64176* / Q8R0W5* / Q8VCC2* / Q8VCT4* / carboxylesterase 1* ...ENSGALG0000003499019
CES2 / carboxylesterase 2 / Ces2f* / Ces2a* / Ces2b* / Ces2e* / Ces2c* / Ces2h* / Ces2g* / Q91WG0* / O00748* / Q8BK48* / Q8QZR3* / carboxyesterase 2B* / carboxylesterase 2G* / carboxylester...ENSGALG0000003892314
CES1* / Ces1h* / Ces1g* / Ces1f* / Ces1e* / Ces1d* / Ces1c* / Ces1b* / Ces1a* / CES4A* / Q91WU0* / P23141* / P23953* / Q5XG92* / Q64176* / Q8R0W5* / Q8VCC2* / Q8VCT4* / carboxylesterase 1* ...ENSGALG000000405589


Protein motifs (from Interpro)
Interpro ID Name
 IPR000460  Neuroligin
 IPR002018  Carboxylesterase, type B
 IPR019819  Carboxylesterase type B, conserved site
 IPR029058  Alpha/Beta hydrolase fold
 IPR030022  Neuroligin-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002087 regulation of respiratory gaseous exchange by neurological system process IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IEA
 biological_processGO:0007158 neuron cell-cell adhesion IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007416 synapse assembly IEA
 biological_processGO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness IEA
 biological_processGO:0016080 synaptic vesicle targeting IEA
 biological_processGO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules IEA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0035418 protein localization to synapse IEA
 biological_processGO:0045184 establishment of protein localization IEA
 biological_processGO:0045664 regulation of neuron differentiation IEA
 biological_processGO:0048488 synaptic vesicle endocytosis IBA
 biological_processGO:0048789 cytoskeletal matrix organization at active zone IEA
 biological_processGO:0050804 modulation of chemical synaptic transmission IEA
 biological_processGO:0050808 synapse organization IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0051965 positive regulation of synapse assembly IEA
 biological_processGO:0060999 positive regulation of dendritic spine development IEA
 biological_processGO:0061002 negative regulation of dendritic spine morphogenesis IEA
 biological_processGO:0072553 terminal button organization IEA
 biological_processGO:0097091 synaptic vesicle clustering IEA
 biological_processGO:0097104 postsynaptic membrane assembly IEA
 biological_processGO:0097105 presynaptic membrane assembly IEA
 biological_processGO:0097113 AMPA glutamate receptor clustering IEA
 biological_processGO:0097115 neurexin clustering involved in presynaptic membrane assembly IEA
 biological_processGO:0097119 postsynaptic density protein 95 clustering IEA
 biological_processGO:0097120 receptor localization to synapse IEA
 biological_processGO:0099560 synaptic membrane adhesion IEA
 biological_processGO:1900244 positive regulation of synaptic vesicle endocytosis IEA
 biological_processGO:1904861 excitatory synapse assembly IEA
 biological_processGO:2000302 positive regulation of synaptic vesicle exocytosis IEA
 biological_processGO:2000310 regulation of NMDA receptor activity IEA
 biological_processGO:2000463 positive regulation of excitatory postsynaptic potential IEA
 biological_processGO:2000809 positive regulation of synaptic vesicle clustering IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0060076 excitatory synapse IEA
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0030165 PDZ domain binding IEA
 molecular_functionGO:0042043 neurexin family protein binding IEA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IBA
 molecular_functionGO:0097110 scaffold protein binding IEA


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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