ENSGALG00000016628


Gallus gallus

Features
Gene ID: ENSGALG00000016628
  
Biological name :NLGN4L
  
Synonyms : neuroligin-4, X-linked / NLGN4L
  
Possible biological names infered from orthology : neuroligin 4, Y-linked / NLGN4X / NLGN4Y / Q8N0W4 / Q8NFZ3
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 126933000
Gene end: 127051569
  
Corresponding Affymetrix probe sets: GgaAffx.10647.1.S1_s_at (Chicken Array)   GgaAffx.10647.3.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000041280
Ensembl peptide - ENSGALP00000061757
Ensembl peptide - ENSGALP00000026789
Ensembl peptide - ENSGALP00000026790
NCBI entrez gene - 428006     See in Manteia.
RefSeq - XM_015274042
RefSeq - XM_015274022
RefSeq - XM_015274025
RefSeq - XM_015274032
RefSeq - XM_015274034
RefSeq - XM_015274037
RefSeq - NM_001171770
RefSeq Peptide - NP_001165241
swissprot - D3WGL6
swissprot - F1NGC1
swissprot - D3WGL4
swissprot - R4GGV5
Ensembl - ENSGALG00000016628
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nlgn4aENSDARG00000079455Danio rerio
 nlgn4bENSDARG00000077761Danio rerio
 NLGN4XENSG00000146938Homo sapiens
 NLGN4YENSG00000165246Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NLGN3 / neuroligin 3 / Q8BYM5* / Q9NZ94*ENSGALG0000000555374
NLGN1 / neuroligin-1 / Q8N2Q7* / Q99K10*ENSGALG0000004093874
BCHE / cholinesterase precursor / P06276* / Q03311* / Cholinesterase * / butyrylcholinesterase*ENSGALG0000003486024
CES1* / Ces1h* / Ces1g* / Ces1f* / Ces1e* / Ces1d* / Ces1c* / Ces1b* / Ces1a* / CES4A* / Q91WU0* / P23141* / P23953* / Q5XG92* / Q64176* / Q8R0W5* / Q8VCC2* / Q8VCT4* / carboxylesterase 1* ...ENSGALG0000003499022
CEL / bile salt-activated lipase precursor / Q64285* / carboxyl ester lipase* / Bile salt-activated lipase *ENSGALG0000003443622
CES2 / carboxylesterase 2 / Ces2f* / Ces2a* / Ces2b* / Ces2e* / Ces2c* / Ces2h* / Ces2g* / Q91WG0* / O00748* / Q8BK48* / Q8QZR3* / carboxyesterase 2B* / carboxylesterase 2G* / carboxylester...ENSGALG0000003892316
CES1* / Ces1h* / Ces1g* / Ces1f* / Ces1e* / Ces1d* / Ces1c* / Ces1b* / Ces1a* / CES4A* / Q91WU0* / P23141* / P23953* / Q5XG92* / Q64176* / Q8R0W5* / Q8VCC2* / Q8VCT4* / carboxylesterase 1* ...ENSGALG0000004055810


Protein motifs (from Interpro)
Interpro ID Name
 IPR000460  Neuroligin
 IPR002018  Carboxylesterase, type B
 IPR019819  Carboxylesterase type B, conserved site
 IPR029058  Alpha/Beta hydrolase fold
 IPR030025  Neuroligin 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007158 neuron cell-cell adhesion IBA
 biological_processGO:0048488 synaptic vesicle endocytosis IBA
 biological_processGO:0050804 modulation of chemical synaptic transmission IBA
 biological_processGO:0050808 synapse organization IEA
 biological_processGO:0097104 postsynaptic membrane assembly IBA
 biological_processGO:0097105 presynaptic membrane assembly IBA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0042043 neurexin family protein binding IEA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IBA


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000016628 NLGN4L / neuroligin-4, X-linked / Q8N0W4* / Q8NFZ3* / NLGN4X* / NLGN4Y* / neuroligin 4, Y-linked*  / complex






 

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contact: otassy@igbmc.fr