ENSDARG00000077761


Danio rerio

Features
Gene ID: ENSDARG00000077761
  
Biological name :nlgn4b
  
Synonyms : neuroligin 4b / nlgn4b
  
Possible biological names infered from orthology : neuroligin 4, X-linked / neuroligin 4, Y-linked / NLGN4X / NLGN4Y / Q8N0W4 / Q8NFZ3
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 55321322
Gene end: 55418196
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000102620
Ensembl peptide - ENSDARP00000144678
Ensembl peptide - ENSDARP00000153805
NCBI entrez gene - 100147967     See in Manteia.
swissprot - F1QK81
ZFIN ID - ZDB-GENE-100309-1
Ensembl - ENSDARG00000077761
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NLGN4LENSGALG00000016628Gallus gallus
 NLGN4XENSG00000146938Homo sapiens
 NLGN4YENSG00000165246Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nlgn4a / neuroligin 4a / NLGN4X* / Q8N0W4* / Q8NFZ3* / NLGN4Y* / neuroligin 4, Y-linked* / neuroligin 4, X-linked*ENSDARG0000007945583
nlgn3a / neuroligin 3a / NLGN3* / Q8BYM5* / Q9NZ94* / neuroligin 3*ENSDARG0000010478671
nlgn1 / neuroligin 1 / Q8N2Q7* / Q99K10*ENSDARG0000007771068
nlgn2a / neuroligin 2a / NLGN2* / Q69ZK9* / Q8NFZ4* / neuroligin 2*ENSDARG0000007732966
nlgn3b / neuroligin 3b / NLGN3* / Q8BYM5* / Q9NZ94* / neuroligin 3*ENSDARG0000006237665
nlgn2b / neuroligin 2b / NLGN2* / Q8NFZ4* / neuroligin 2*ENSDARG0000007925164
ache / Q9DDE3 / acetylcholinesterase / P21836* / P22303* / acetylcholinesterase (Cartwright blood group)*ENSDARG0000003179625
ces3 / carboxylesterase 3 / CES1* / CES2* / Ces2h* / Ces2g* / Ces2f* / Ces2e* / Ces2c* / Ces2b* / Ces2a* / Ces1h* / Ces1g* / Ces1f* / Ces1a* / Ces1b* / Ces1c* / Ces1e* / Ces1d* / CES5A* / C...ENSDARG0000004159521
ces2 / carboxylesterase 2 (intestine, liver) / CES1* / CES3* / Ces2h* / Ces2g* / Ces2f* / Ces2e* / Ces2c* / Ces2b* / Ces2a* / Ces1h* / Ces1g* / Ces1f* / Ces1e* / Ces1a* / Ces1b* / Ces1d* / ...ENSDARG0000004156921
cel.2 / carboxyl ester lipase, tandem duplicate 2 / CEL* / Q64285* / carboxyl ester lipase* / Bile salt-activated lipase *ENSDARG0000002982221
cel.1 / carboxyl ester lipase, tandem duplicate 1 / CEL* / Q64285* / carboxyl ester lipase* / Bile salt-activated lipase *ENSDARG0000001749020
si:ch211-93f2.1 / CES1* / CES2* / CES3* / Ces2h* / Ces2g* / Ces2f* / Ces2e* / Ces2c* / Ces2b* / Ces2a* / Ces1h* / Ces1g* / Ces1f* / Ces1a* / Ces1b* / Ces1c* / Ces1e* / Ces1d* / CES5A* / CES...ENSDARG0000010172617
si:ch211-93f2.1 / CES1* / CES3* / CES2* / CES4A* / CES5A* / Q6NT32* / P23141* / Q5XG92* / Q6UWW8* / O00748* / carboxylesterase 1* / carboxylesterase 2* / carboxylesterase 3* / carboxylester...ENSDARG0000010481814


Protein motifs (from Interpro)
Interpro ID Name
 IPR000460  Neuroligin
 IPR002018  Carboxylesterase, type B
 IPR019819  Carboxylesterase type B, conserved site
 IPR029058  Alpha/Beta hydrolase fold
 IPR030025  Neuroligin 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007158 neuron cell-cell adhesion IBA
 biological_processGO:0048488 synaptic vesicle endocytosis IBA
 biological_processGO:0050804 modulation of chemical synaptic transmission IBA
 biological_processGO:0097104 postsynaptic membrane assembly IBA
 biological_processGO:0097105 presynaptic membrane assembly IBA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0009986 cell surface IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0045202 synapse IBA
 molecular_functionGO:0042043 neurexin family protein binding IBA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IBA


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000077761 nlgn4b / neuroligin 4b / NLGN4X* / Q8N0W4* / Q8NFZ3* / NLGN4Y* / neuroligin 4, Y-linked* / neuroligin 4, X-linked*  / complex
 ENSDARG00000079455 nlgn4a / neuroligin 4a / NLGN4X* / Q8N0W4* / Q8NFZ3* / NLGN4Y* / neuroligin 4, Y-linked* / neuroligin 4, X-linked*  / complex






 

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