Manteia

ENSDARG00000079455

Danio rerio

Features

Gene ID:	ENSDARG00000079455

Biological name :	nlgn4a

Synonyms :	neuroligin 4a / nlgn4a

Possible biological names infered from orthology :	neuroligin 4, X-linked / neuroligin 4, Y-linked / NLGN4X / NLGN4Y / Q8N0W4 / Q8NFZ3

Species:	Danio rerio

Chr. number:	1
Strand:	1
Band:
Gene start:	32521469
Gene end:	32693950

Corresponding Affymetrix probe sets:	Dr.12827.1.A1_at (Zebrafish Array) Dr.12913.1.A1_at (Zebrafish Array)

Cross references:	Ensembl peptide - ENSDARP00000103677 Ensembl peptide - ENSDARP00000110247 Ensembl peptide - ENSDARP00000126721 NCBI entrez gene - 561122 See in Manteia. RefSeq - XM_009292174 swissprot - F1Q7W8 swissprot - F1QVL5 swissprot - R4GE10 ZFIN ID - ZDB-GENE-100309-2 Ensembl - ENSDARG00000079455

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
NLGN4L	ENSGALG00000016628	Gallus gallus
NLGN4X	ENSG00000146938	Homo sapiens
NLGN4Y	ENSG00000165246	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
nlgn4b / neuroligin 4b / NLGN4X* / Q8N0W4* / Q8NFZ3* / NLGN4Y* / neuroligin 4, Y-linked* / neuroligin 4, X-linked*	ENSDARG00000077761	78
nlgn3a / neuroligin 3a / NLGN3* / Q8BYM5* / Q9NZ94* / neuroligin 3*	ENSDARG00000104786	70
nlgn1 / neuroligin 1 / Q8N2Q7* / Q99K10*	ENSDARG00000077710	69
nlgn2a / neuroligin 2a / NLGN2* / Q69ZK9* / Q8NFZ4* / neuroligin 2*	ENSDARG00000077329	64
nlgn3b / neuroligin 3b / NLGN3* / Q8BYM5* / Q9NZ94* / neuroligin 3*	ENSDARG00000062376	63
nlgn2b / neuroligin 2b / NLGN2* / Q8NFZ4* / neuroligin 2*	ENSDARG00000079251	62
ache / Q9DDE3 / acetylcholinesterase / P21836* / P22303* / acetylcholinesterase (Cartwright blood group)*	ENSDARG00000031796	24
ces3 / carboxylesterase 3 / CES1* / CES2* / Ces2h* / Ces2g* / Ces2f* / Ces2e* / Ces2c* / Ces2b* / Ces2a* / Ces1h* / Ces1g* / Ces1f* / Ces1a* / Ces1b* / Ces1c* / Ces1e* / Ces1d* / CES5A* / C...	ENSDARG00000041595	21
ces2 / carboxylesterase 2 (intestine, liver) / CES1* / CES3* / Ces2h* / Ces2g* / Ces2f* / Ces2e* / Ces2c* / Ces2b* / Ces2a* / Ces1h* / Ces1g* / Ces1f* / Ces1e* / Ces1a* / Ces1b* / Ces1d* / ...	ENSDARG00000041569	21
cel.2 / carboxyl ester lipase, tandem duplicate 2 / CEL* / Q64285* / carboxyl ester lipase* / Bile salt-activated lipase *	ENSDARG00000029822	20
cel.1 / carboxyl ester lipase, tandem duplicate 1 / CEL* / Q64285* / carboxyl ester lipase* / Bile salt-activated lipase *	ENSDARG00000017490	19
si:ch211-93f2.1 / CES1* / CES2* / CES3* / Ces2h* / Ces2g* / Ces2f* / Ces2e* / Ces2c* / Ces2b* / Ces2a* / Ces1h* / Ces1g* / Ces1f* / Ces1a* / Ces1b* / Ces1c* / Ces1e* / Ces1d* / CES5A* / CES...	ENSDARG00000101726	16
si:ch211-93f2.1 / CES1* / CES3* / CES2* / CES4A* / CES5A* / Q6NT32* / P23141* / Q5XG92* / Q6UWW8* / O00748* / carboxylesterase 1* / carboxylesterase 2* / carboxylesterase 3* / carboxylester...	ENSDARG00000104818	13

Protein motifs (from Interpro)

Interpro ID	Name
IPR000460	Neuroligin
IPR002018	Carboxylesterase, type B
IPR019819	Carboxylesterase type B, conserved site
IPR029058	Alpha/Beta hydrolase fold
IPR030025	Neuroligin 4

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007158	neuron cell-cell adhesion	IBA
biological_process	GO:0048488	synaptic vesicle endocytosis	IBA
biological_process	GO:0050804	modulation of chemical synaptic transmission	IBA
biological_process	GO:0097104	postsynaptic membrane assembly	IBA
biological_process	GO:0097105	presynaptic membrane assembly	IBA
cellular_component	GO:0005887	integral component of plasma membrane	IBA
cellular_component	GO:0009986	cell surface	IBA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:0045202	synapse	IBA
molecular_function	GO:0042043	neurexin family protein binding	IEA
molecular_function	GO:0052689	carboxylic ester hydrolase activity	IBA

Pathways (from Reactome)

Pathway description

Neurexins and neuroligins

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSDARG00000079455	nlgn4a / neuroligin 4a / NLGN4X* / Q8N0W4* / Q8NFZ3* / NLGN4Y* / neuroligin 4, Y-linked* / neuroligin 4, X-linked*	/ complex
ENSDARG00000077761	nlgn4b / neuroligin 4b / NLGN4X* / Q8N0W4* / Q8NFZ3* / NLGN4Y* / neuroligin 4, Y-linked* / neuroligin 4, X-linked*	/ complex

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr