ENSDARG00000077329


Danio rerio

Features
Gene ID: ENSDARG00000077329
  
Biological name :nlgn2a
  
Synonyms : neuroligin 2a / nlgn2a
  
Possible biological names infered from orthology : neuroligin 2 / NLGN2 / Q69ZK9 / Q8NFZ4
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 21940857
Gene end: 22132265
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000111294
Ensembl peptide - ENSDARP00000103229
NCBI entrez gene - 556158     See in Manteia.
RefSeq - XM_021477537
RefSeq - NM_001166329
RefSeq Peptide - NP_001159801
swissprot - F1QJV3
swissprot - F1Q9C0
ZFIN ID - ZDB-GENE-090918-2
Ensembl - ENSDARG00000077329
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NLGN2ENSG00000169992Homo sapiens
 Nlgn2ENSMUSG00000051790Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nlgn2b / neuroligin 2b / NLGN2* / Q8NFZ4* / neuroligin 2*ENSDARG0000007925182
nlgn1 / neuroligin 1 / Q8N2Q7* / Q99K10*ENSDARG0000007771067
nlgn4a / neuroligin 4a / NLGN4X* / Q8N0W4* / Q8NFZ3* / NLGN4Y* / neuroligin 4, Y-linked* / neuroligin 4, X-linked*ENSDARG0000007945565
nlgn3a / neuroligin 3a / NLGN3* / Q8BYM5* / Q9NZ94* / neuroligin 3*ENSDARG0000010478664
nlgn4b / neuroligin 4b / NLGN4X* / Q8N0W4* / Q8NFZ3* / NLGN4Y* / neuroligin 4, Y-linked* / neuroligin 4, X-linked*ENSDARG0000007776163
nlgn3b / neuroligin 3b / NLGN3* / Q8BYM5* / Q9NZ94* / neuroligin 3*ENSDARG0000006237659
ache / Q9DDE3 / acetylcholinesterase / P21836* / P22303* / acetylcholinesterase (Cartwright blood group)*ENSDARG0000003179624
ces2 / carboxylesterase 2 (intestine, liver) / CES1* / CES3* / Ces2h* / Ces2g* / Ces2f* / Ces2e* / Ces2c* / Ces2b* / Ces2a* / Ces1h* / Ces1g* / Ces1f* / Ces1e* / Ces1a* / Ces1b* / Ces1d* / ...ENSDARG0000004156921
ces3 / carboxylesterase 3 / CES1* / CES2* / Ces2h* / Ces2g* / Ces2f* / Ces2e* / Ces2c* / Ces2b* / Ces2a* / Ces1h* / Ces1g* / Ces1f* / Ces1a* / Ces1b* / Ces1c* / Ces1e* / Ces1d* / CES5A* / C...ENSDARG0000004159521
cel.2 / carboxyl ester lipase, tandem duplicate 2 / CEL* / Q64285* / carboxyl ester lipase* / Bile salt-activated lipase *ENSDARG0000002982220
cel.1 / carboxyl ester lipase, tandem duplicate 1 / CEL* / Q64285* / carboxyl ester lipase* / Bile salt-activated lipase *ENSDARG0000001749020
si:ch211-93f2.1 / CES1* / CES2* / CES3* / Ces2h* / Ces2g* / Ces2f* / Ces2e* / Ces2c* / Ces2b* / Ces2a* / Ces1h* / Ces1g* / Ces1f* / Ces1a* / Ces1b* / Ces1c* / Ces1e* / Ces1d* / CES5A* / CES...ENSDARG0000010172616
si:ch211-93f2.1 / CES1* / CES3* / CES2* / CES4A* / CES5A* / Q6NT32* / P23141* / Q5XG92* / Q6UWW8* / O00748* / carboxylesterase 1* / carboxylesterase 2* / carboxylesterase 3* / carboxylester...ENSDARG0000010481813


Protein motifs (from Interpro)
Interpro ID Name
 IPR000460  Neuroligin
 IPR002018  Carboxylesterase, type B
 IPR019819  Carboxylesterase type B, conserved site
 IPR029058  Alpha/Beta hydrolase fold
 IPR030023  Neuroligin-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007158 neuron cell-cell adhesion IBA
 biological_processGO:0048488 synaptic vesicle endocytosis IBA
 biological_processGO:0050804 modulation of chemical synaptic transmission IEA
 biological_processGO:0050808 synapse organization IEA
 biological_processGO:0097104 postsynaptic membrane assembly IBA
 biological_processGO:0097105 presynaptic membrane assembly IBA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0045202 synapse IBA
 cellular_componentGO:0060077 inhibitory synapse IEA
 molecular_functionGO:0042043 neurexin family protein binding IEA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IBA


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000079251 nlgn2b / neuroligin 2b / NLGN2* / Q8NFZ4* / neuroligin 2*  / complex
 ENSDARG00000077329 nlgn2a / neuroligin 2a / NLGN2* / Q69ZK9* / Q8NFZ4* / neuroligin 2*  / complex






 

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