ENSGALG00000041348


Gallus gallus

Features
Gene ID: ENSGALG00000041348
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology : glutamate ionotropic receptor NMDA type subunit 2B / glutamate receptor, ionotropic, NMDA2B (epsilon 2) / GRIN2B / Q13224
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 48520716
Gene end: 48659867
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000044998
swissprot - A0A1D5NXA4
Ensembl - ENSGALG00000041348
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 grin2bbENSDARG00000030376Danio rerio
 LO018552.1ENSDARG00000079348Danio rerio
 GRIN2BENSG00000273079Homo sapiens
 Grin2bENSMUSG00000030209Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GRIN2A / glutamate ionotropic receptor NMDA type subunit 2A / P35436* / Q12879* / Glutamate receptor ionotropic, NMDA 2A *ENSGALG0000000727861
GRIN2C / glutamate ionotropic receptor NMDA type subunit 2C / Q01098* / Q14957* / Glutamate receptor ionotropic, NMDA 2C *ENSGALG0000002741547
GRIN3A / glutamate ionotropic receptor NMDA type subunit 3A / Q8TCU5*ENSGALG0000001555121
GRIN1 / glutamate ionotropic receptor NMDA type subunit 1 / P35438* / Q05586* / Glutamate receptor ionotropic, NMDA 1 *ENSGALG0000000889821
GRIN3B / glutamate ionotropic receptor NMDA type subunit 3B / O60391* / Q91ZU9* / Glutamate receptor ionotropic, NMDA 3B *ENSGALG0000002624120
GRIK2 / glutamate ionotropic receptor kainate type subunit 2 / P39087* / Q13002* / Glutamate receptor ionotropic, kainate 2 *ENSGALG0000001543418
GRIK4 / glutamate ionotropic receptor kainate type subunit 4 / Q16099* / Q8BMF5* / Glutamate receptor ionotropic, kainate 4 *ENSGALG0000000663818
GRIA4 / glutamate receptor 4 isoform 1 precursor / P48058* / Q9Z2W8* / glutamate receptor, ionotropic, AMPA4 (alpha 4)* / glutamate ionotropic receptor AMPA type subunit 4*ENSGALG0000003899518
GRIA1 / glutamate ionotropic receptor AMPA type subunit 1 / P23818* / P42261* / Glutamate receptor 1 *ENSGALG0000000408318
GRIK3 / glutamate ionotropic receptor kainate type subunit 3 / B1AS29* / Q13003* / Glutamate receptor ionotropic, kainate 3 *ENSGALG0000000209818
GRIA3 / glutamate receptor 3 isoform 2 precursor / P42263* / Q9Z2W9* / glutamate ionotropic receptor AMPA type subunit 3* / Mus musculus glutamate receptor, ionotropic, AMPA3 (alpha 3) (Gr...ENSGALG0000003410918
GRIK1 / glutamate ionotropic receptor kainate type subunit 1 / P39086* / Mus musculus glutamate receptor, ionotropic, kainate 1 (Grik1), transcript variant 3, mRNA.*ENSGALG0000001583517
GRIA2 / glutamate receptor 2 isoform 1 precursor / P42262* / glutamate receptor 2 isoform 3 * / glutamate ionotropic receptor AMPA type subunit 2*ENSGALG0000000940517
GRID1 / glutamate ionotropic receptor delta type subunit 1 / Q61627* / Q9ULK0* / Glutamate receptor ionotropic, delta-1 *ENSGALG0000003736615
GRID2 / glutamate ionotropic receptor delta type subunit 2 / O43424* / Q61625* / Glutamate receptor ionotropic, delta-2 *ENSGALG0000001039715
KBP / P19439 / Probable glutamate receptor ENSGALG000000011729
GRIN2B* / Q13224* / glutamate ionotropic receptor NMDA type subunit 2B* / glutamate receptor, ionotropic, NMDA2B (epsilon 2)*ENSGALG000000118093


Protein motifs (from Interpro)
Interpro ID Name
 IPR001320  Ionotropic glutamate receptor
 IPR001828  Receptor, ligand binding region
 IPR019594  Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
 IPR028082  Periplasmic binding protein-like I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0035235 ionotropic glutamate receptor signaling pathway IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004970 ionotropic glutamate receptor activity IEA
 molecular_functionGO:0005234 extracellularly glutamate-gated ion channel activity IEA


Pathways (from Reactome)
Pathway description
EPHB-mediated forward signaling
Unblocking of NMDA receptor, glutamate binding and activation
CREB phosphorylation through the activation of CaMKII
Ras activation upon Ca2+ influx through NMDA receptor
RAF/MAP kinase cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr