ENSGALG00000038995


Gallus gallus

Features
Gene ID: ENSGALG00000038995
  
Biological name :GRIA4
  
Synonyms : glutamate receptor 4 isoform 1 precursor / GRIA4
  
Possible biological names infered from orthology : glutamate ionotropic receptor AMPA type subunit 4 / glutamate receptor, ionotropic, AMPA4 (alpha 4) / P48058 / Q9Z2W8
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 181192418
Gene end: 181414573
  
Corresponding Affymetrix probe sets: Gga.2741.1.S2_at (Chicken Array)   Gga.2741.4.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051051
Ensembl peptide - ENSGALP00000057500
Ensembl peptide - ENSGALP00000053498
Ensembl peptide - ENSGALP00000052861
NCBI entrez gene - 396137     See in Manteia.
RefSeq - XM_015277725
RefSeq - NM_001113186
RefSeq - NM_205214
RefSeq Peptide - NP_990545
RefSeq Peptide - NP_001106657
swissprot - A0A1D5PE52
swissprot - A0A1D5PX10
swissprot - A0A1D5PKY5
swissprot - A0A1D5PJ69
Ensembl - ENSGALG00000038995
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GRIA4ENSG00000152578Homo sapiens
 Gria4ENSMUSG00000025892Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GRIA3 / glutamate receptor 3 isoform 2 precursor / P42263* / Q9Z2W9* / glutamate ionotropic receptor AMPA type subunit 3* / Mus musculus glutamate receptor, ionotropic, AMPA3 (alpha 3) (Gr...ENSGALG0000003410969
GRIA2 / glutamate receptor 2 isoform 1 precursor / P42262* / glutamate receptor 2 isoform 3 * / glutamate ionotropic receptor AMPA type subunit 2*ENSGALG0000000940567
GRIA1 / glutamate ionotropic receptor AMPA type subunit 1 / P23818* / P42261* / Glutamate receptor 1 *ENSGALG0000000408363
GRIK2 / glutamate ionotropic receptor kainate type subunit 2 / P39087* / Q13002* / Glutamate receptor ionotropic, kainate 2 *ENSGALG0000001543436
GRIK1 / glutamate ionotropic receptor kainate type subunit 1 / P39086* / Mus musculus glutamate receptor, ionotropic, kainate 1 (Grik1), transcript variant 3, mRNA.*ENSGALG0000001583535
GRIK3 / glutamate ionotropic receptor kainate type subunit 3 / B1AS29* / Q13003* / Glutamate receptor ionotropic, kainate 3 *ENSGALG0000000209834
GRIK4 / glutamate ionotropic receptor kainate type subunit 4 / Q16099* / Q8BMF5* / Glutamate receptor ionotropic, kainate 4 *ENSGALG0000000663829
GRID1 / glutamate ionotropic receptor delta type subunit 1 / Q61627* / Q9ULK0* / Glutamate receptor ionotropic, delta-1 *ENSGALG0000003736625
GRID2 / glutamate ionotropic receptor delta type subunit 2 / O43424* / Q61625* / Glutamate receptor ionotropic, delta-2 *ENSGALG0000001039722
GRIN2C / glutamate ionotropic receptor NMDA type subunit 2C / Q01098* / Q14957* / Glutamate receptor ionotropic, NMDA 2C *ENSGALG0000002741520
GRIN1 / glutamate ionotropic receptor NMDA type subunit 1 / P35438* / Q05586* / Glutamate receptor ionotropic, NMDA 1 *ENSGALG0000000889819
GRIN2A / glutamate ionotropic receptor NMDA type subunit 2A / P35436* / Q12879* / Glutamate receptor ionotropic, NMDA 2A *ENSGALG0000000727819
GRIN3B / glutamate ionotropic receptor NMDA type subunit 3B / O60391* / Q91ZU9* / Glutamate receptor ionotropic, NMDA 3B *ENSGALG0000002624118
KBP / P19439 / Probable glutamate receptor ENSGALG0000000117218
GRIN3A / glutamate ionotropic receptor NMDA type subunit 3A / Q8TCU5*ENSGALG0000001555116
GRIN2B* / Q13224* / glutamate ionotropic receptor NMDA type subunit 2B* / glutamate receptor, ionotropic, NMDA2B (epsilon 2)*ENSGALG0000004134812
GRIN2B* / Q13224* / glutamate ionotropic receptor NMDA type subunit 2B* / glutamate receptor, ionotropic, NMDA2B (epsilon 2)*ENSGALG000000118098


Protein motifs (from Interpro)
Interpro ID Name
 IPR001320  Ionotropic glutamate receptor
 IPR001508  Ionotropic glutamate receptor, metazoa
 IPR001828  Receptor, ligand binding region
 IPR019594  Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
 IPR028082  Periplasmic binding protein-like I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0035235 ionotropic glutamate receptor signaling pathway IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004970 ionotropic glutamate receptor activity IEA
 molecular_functionGO:0004971 AMPA glutamate receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005234 extracellularly glutamate-gated ion channel activity IEA


Pathways (from Reactome)
Pathway description
Activation of AMPA receptors
Trafficking of GluR2-containing AMPA receptors
Unblocking of NMDA receptor, glutamate binding and activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004083 GRIA1 / glutamate ionotropic receptor AMPA type subunit 1 / P23818* / P42261* / Glutamate receptor 1 *  / reaction / complex
 ENSGALG00000008432 AP2M1 / Q5ZMP6 / AP-2 complex subunit mu / P84091* / Q96CW1* / adaptor related protein complex 2 mu 1 subunit*  / reaction
 ENSGALG00000027415 GRIN2C / glutamate ionotropic receptor NMDA type subunit 2C / Q01098* / Q14957* / Glutamate receptor ionotropic, NMDA 2C *  / reaction
 ENSGALG00000038995 GRIA4 / glutamate receptor 4 isoform 1 precursor / P48058* / Q9Z2W8* / glutamate receptor, ionotropic, AMPA4 (alpha 4)* / glutamate ionotropic receptor AMPA type subunit 4*  / reaction / complex
 ENSGALG00000008898 GRIN1 / glutamate ionotropic receptor NMDA type subunit 1 / P35438* / Q05586* / Glutamate receptor ionotropic, NMDA 1 *  / reaction
 ENSGALG00000040724 AKAP9 / A-kinase anchoring protein 9 / Q99996*  / reaction
 ENSGALG00000000314 NEFL / neurofilament light / P07196* / P08551* / Neurofilament light polypeptide *  / reaction
 ENSGALG00000007278 GRIN2A / glutamate ionotropic receptor NMDA type subunit 2A / P35436* / Q12879* / Glutamate receptor ionotropic, NMDA 2A *  / reaction
 ENSGALG00000014463 ACTN2 / P20111 / Alpha-actinin-2 / P35609* / Q9JI91* / actinin alpha 2*  / reaction
 ENSGALG00000041823 PICK1 / protein interacting with PRKCA 1 / Q9NRD5* / protein interacting with C kinase 1*  / reaction
 ENSGALG00000005621 CAMK2A / calcium/calmodulin-dependent protein kinase type II subunit alpha / P11798* / Q9UQM7* / calcium/calmodulin dependent protein kinase II alpha*  / reaction
 ENSGALG00000042125 AP2B1 / adaptor related protein complex 2 beta 1 subunit / P63010* / Q9DBG3* / AP-2 complex subunit beta *  / reaction






 

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