ENSGALG00000015434


Gallus gallus

Features
Gene ID: ENSGALG00000015434
  
Biological name :GRIK2
  
Synonyms : glutamate ionotropic receptor kainate type subunit 2 / GRIK2
  
Possible biological names infered from orthology : Glutamate receptor ionotropic, kainate 2 / P39087 / Q13002
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 70383444
Gene end: 70747010
  
Corresponding Affymetrix probe sets: GgaAffx.9829.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051473
Ensembl peptide - ENSGALP00000024847
NCBI entrez gene - 428628     See in Manteia.
RefSeq - XM_015284535
RefSeq - XM_015284533
RefSeq - XM_015284534
swissprot - F1NU20
swissprot - A0A1D5PFB0
Ensembl - ENSGALG00000015434
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GRIK2ENSDARG00000113771Danio rerio
 GRIK2ENSG00000164418Homo sapiens
 Grik2ENSMUSG00000056073Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GRIK3 / glutamate ionotropic receptor kainate type subunit 3 / B1AS29* / Q13003* / Glutamate receptor ionotropic, kainate 3 *ENSGALG0000000209879
GRIK1 / glutamate ionotropic receptor kainate type subunit 1 / P39086* / Mus musculus glutamate receptor, ionotropic, kainate 1 (Grik1), transcript variant 3, mRNA.*ENSGALG0000001583577
GRIA2 / glutamate receptor 2 isoform 1 precursor / P42262* / glutamate receptor 2 isoform 3 * / glutamate ionotropic receptor AMPA type subunit 2*ENSGALG0000000940538
GRIA1 / glutamate ionotropic receptor AMPA type subunit 1 / P23818* / P42261* / Glutamate receptor 1 *ENSGALG0000000408338
GRIA3 / glutamate receptor 3 isoform 2 precursor / P42263* / Q9Z2W9* / glutamate ionotropic receptor AMPA type subunit 3* / Mus musculus glutamate receptor, ionotropic, AMPA3 (alpha 3) (Gr...ENSGALG0000003410938
GRIA4 / glutamate receptor 4 isoform 1 precursor / P48058* / Q9Z2W8* / glutamate receptor, ionotropic, AMPA4 (alpha 4)* / glutamate ionotropic receptor AMPA type subunit 4*ENSGALG0000003899537
GRIK4 / glutamate ionotropic receptor kainate type subunit 4 / Q16099* / Q8BMF5* / Glutamate receptor ionotropic, kainate 4 *ENSGALG0000000663837
GRID1 / glutamate ionotropic receptor delta type subunit 1 / Q61627* / Q9ULK0* / Glutamate receptor ionotropic, delta-1 *ENSGALG0000003736627
GRID2 / glutamate ionotropic receptor delta type subunit 2 / O43424* / Q61625* / Glutamate receptor ionotropic, delta-2 *ENSGALG0000001039725
GRIN2A / glutamate ionotropic receptor NMDA type subunit 2A / P35436* / Q12879* / Glutamate receptor ionotropic, NMDA 2A *ENSGALG0000000727821
GRIN1 / glutamate ionotropic receptor NMDA type subunit 1 / P35438* / Q05586* / Glutamate receptor ionotropic, NMDA 1 *ENSGALG0000000889820
GRIN2C / glutamate ionotropic receptor NMDA type subunit 2C / Q01098* / Q14957* / Glutamate receptor ionotropic, NMDA 2C *ENSGALG0000002741520
KBP / P19439 / Probable glutamate receptor ENSGALG0000000117220
GRIN3B / glutamate ionotropic receptor NMDA type subunit 3B / O60391* / Q91ZU9* / Glutamate receptor ionotropic, NMDA 3B *ENSGALG0000002624118
GRIN3A / glutamate ionotropic receptor NMDA type subunit 3A / Q8TCU5*ENSGALG0000001555117
GRIN2B* / Q13224* / glutamate ionotropic receptor NMDA type subunit 2B* / glutamate receptor, ionotropic, NMDA2B (epsilon 2)*ENSGALG0000004134812
GRIN2B* / Q13224* / glutamate ionotropic receptor NMDA type subunit 2B* / glutamate receptor, ionotropic, NMDA2B (epsilon 2)*ENSGALG000000118098


Protein motifs (from Interpro)
Interpro ID Name
 IPR001320  Ionotropic glutamate receptor
 IPR001508  Ionotropic glutamate receptor, metazoa
 IPR001828  Receptor, ligand binding region
 IPR019594  Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
 IPR028082  Periplasmic binding protein-like I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001662 behavioral fear response IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006874 cellular calcium ion homeostasis IEA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0007268 chemical synaptic transmission IEA
 biological_processGO:0019228 neuronal action potential IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0035235 ionotropic glutamate receptor signaling pathway IEA
 biological_processGO:0035249 synaptic transmission, glutamatergic IEA
 biological_processGO:0042391 regulation of membrane potential IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0048169 regulation of long-term neuronal synaptic plasticity IEA
 biological_processGO:0048172 regulation of short-term neuronal synaptic plasticity IEA
 biological_processGO:0050804 modulation of chemical synaptic transmission IEA
 biological_processGO:0050806 positive regulation of synaptic transmission IEA
 biological_processGO:0051967 negative regulation of synaptic transmission, glutamatergic IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0060080 inhibitory postsynaptic potential IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0032983 kainate selective glutamate receptor complex IEA
 cellular_componentGO:0042734 presynaptic membrane IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004970 ionotropic glutamate receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005234 extracellularly glutamate-gated ion channel activity IEA
 molecular_functionGO:0015277 kainate selective glutamate receptor activity IEA


Pathways (from Reactome)
Pathway description
Activation of Na-permeable kainate receptors
Activation of Ca-permeable Kainate Receptor


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000006638 GRIK4 / glutamate ionotropic receptor kainate type subunit 4 / Q16099* / Q8BMF5* / Glutamate receptor ionotropic, kainate 4 *  / complex
 ENSGALG00000015434 GRIK2 / glutamate ionotropic receptor kainate type subunit 2 / P39087* / Q13002* / Glutamate receptor ionotropic, kainate 2 *  / reaction / complex
 ENSGALG00000002098 GRIK3 / glutamate ionotropic receptor kainate type subunit 3 / B1AS29* / Q13003* / Glutamate receptor ionotropic, kainate 3 *  / complex






 

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