ENSGALG00000041907


Gallus gallus

Features
Gene ID: ENSGALG00000041907
  
Biological name :CDK5R1
  
Synonyms : CDK5R1 / cyclin dependent kinase 5 regulatory subunit 1
  
Possible biological names infered from orthology : Cyclin-dependent kinase 5 activator 1 Cyclin-dependent kinase 5 activator 1, p35 Cyclin-dependent kinase 5 activator 1, p25 / P61809 / Q15078
  
Species: Gallus gallus
  
Chr. number: 27
Strand: -1
Band:
Gene start: 1657762
Gene end: 1658664
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000047031
NCBI entrez gene - 107055275     See in Manteia.
RefSeq - XM_015299298
swissprot - A0A1D5P2X9
Ensembl - ENSGALG00000041907
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdk5r1aENSDARG00000037916Danio rerio
 cdk5r1bENSDARG00000045087Danio rerio
 CDK5R1ENSG00000176749Homo sapiens
 Cdk5r1ENSMUSG00000048895Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CDK5R2 / cyclin dependent kinase 5 regulatory subunit 2 / O35926* / Q13319* / Cyclin-dependent kinase 5 activator 2 *ENSGALG0000002572955


Protein motifs (from Interpro)
Interpro ID Name
 IPR004944  Cyclin-dependent kinase 5 activator
 IPR013763  Cyclin-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0007158 neuron cell-cell adhesion IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0007413 axonal fasciculation IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IEA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IEA
 biological_processGO:0021549 cerebellum development IEA
 biological_processGO:0021722 superior olivary nucleus maturation IEA
 biological_processGO:0021766 hippocampus development IEA
 biological_processGO:0021799 cerebral cortex radially oriented cell migration IEA
 biological_processGO:0021819 layer formation in cerebral cortex IEA
 biological_processGO:0030517 negative regulation of axon extension IEA
 biological_processGO:0032956 regulation of actin cytoskeleton organization IEA
 biological_processGO:0042501 serine phosphorylation of STAT protein IEA
 biological_processGO:0045860 positive regulation of protein kinase activity IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0048013 ephrin receptor signaling pathway IEA
 biological_processGO:0061001 regulation of dendritic spine morphogenesis IEA
 biological_processGO:0070507 regulation of microtubule cytoskeleton organization IEA
 biological_processGO:0071158 positive regulation of cell cycle arrest IEA
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity IEA
 biological_processGO:0090314 positive regulation of protein targeting to membrane IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016533 protein kinase 5 complex IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0002020 protease binding IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0016534 cyclin-dependent protein kinase 5 activator activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0035255 ionotropic glutamate receptor binding IEA
 molecular_functionGO:0043539 protein serine/threonine kinase activator activity IEA
 molecular_functionGO:0051015 actin filament binding IEA


Pathways (from Reactome)
Pathway description
CRMPs in Sema3A signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000015022 FYN / tyrosine-protein kinase Fyn / P06241* / P39688* / FYN proto-oncogene, Src family tyrosine kinase*  / complex
 ENSGALG00000001264 PLXNA2 / plexin A2 / O75051* / P70207*  / complex
 ENSGALG00000006097 PLXNA1 / plexin A1 / P70206* / Q9UIW2*  / complex






 

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