ENSGALG00000043711


Gallus gallus

Features
Gene ID: ENSGALG00000043711
  
Biological name :AGO3
  
Synonyms : AGO3 / protein argonaute-3
  
Possible biological names infered from orthology : argonaute 3, RISC catalytic component / Q8CJF9 / Q9H9G7
  
Species: Gallus gallus
  
Chr. number: 23
Strand: -1
Band:
Gene start: 4174718
Gene end: 4196516
  
Corresponding Affymetrix probe sets: GgaAffx.11873.1.S1_s_at (Chicken Array)   GgaAffx.1501.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049953
Ensembl peptide - ENSGALP00000062841
Ensembl peptide - ENSGALP00000061434
Ensembl peptide - ENSGALP00000052719
NCBI entrez gene - 419628     See in Manteia.
RefSeq - NM_001030900
RefSeq Peptide - NP_001026071
swissprot - A0A1L1RVH9
swissprot - A0A1L1RRL4
swissprot - A0A1D5PIT3
swissprot - F1P3Z0
Ensembl - ENSGALG00000043711
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ago3aENSDARG00000059888Danio rerio
 ago3bENSDARG00000063079Danio rerio
 AGO3ENSG00000126070Homo sapiens
 Ago3ENSMUSG00000028842Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AGO1 / argonaute 1, RISC catalytic component / Q8CJG1* / Q9UL18* / Protein argonaute-1 *ENSGALG0000000224984
AGO4 / Q5ZMW0 / Protein argonaute-4 / Q8CJF8* / Q9HCK5* / argonaute 4, RISC catalytic component*ENSGALG0000003971382
AGO2 / argonaute 2, RISC catalytic component / Q8CJG0* / Q9UKV8* / Protein argonaute-2 *ENSGALG0000004095779
A6N7Y9 / PIWIL1 / Piwi-like protein 1 / Q96J94* / Q9JMB7* / piwi like RNA-mediated gene silencing 1*ENSGALG0000000264523


Protein motifs (from Interpro)
Interpro ID Name
 IPR003100  PAZ domain
 IPR003165  Piwi domain
 IPR012337  Ribonuclease H-like superfamily
 IPR014811  Argonaute, linker 1 domain
 IPR028603  Protein argonaute-3
 IPR032472  Argonaute linker 2 domain
 IPR032473  Protein argonaute, Mid domain
 IPR032474  Protein argonaute, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006402 mRNA catabolic process IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0010501 RNA secondary structure unwinding IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0031054 pre-miRNA processing IEA
 biological_processGO:0035196 production of miRNAs involved in gene silencing by miRNA IEA
 biological_processGO:0035278 miRNA mediated inhibition of translation IEA
 biological_processGO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA IEA
 biological_processGO:0072091 regulation of stem cell proliferation IEA
 biological_processGO:1901224 positive regulation of NIK/NF-kappaB signaling IEA
 cellular_componentGO:0000794 condensed nuclear chromosome IEA
 cellular_componentGO:0000932 P-body IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016442 RISC complex IEA
 cellular_componentGO:0035068 micro-ribonucleoprotein complex IEA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IEA
 cellular_componentGO:0070578 RISC-loading complex IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding IEA
 molecular_functionGO:0003727 single-stranded RNA binding IEA
 molecular_functionGO:0035198 miRNA binding IEA


Pathways (from Reactome)
Pathway description
MicroRNA (miRNA) biogenesis
Small interfering RNA (siRNA) biogenesis
Post-transcriptional silencing by small RNAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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