ENSGALG00000039713


Gallus gallus

Features
Gene ID: ENSGALG00000039713
  
Biological name :AGO4
  
Synonyms : AGO4 / Protein argonaute-4 / Q5ZMW0
  
Possible biological names infered from orthology : argonaute 4, RISC catalytic component / Q8CJF8 / Q9HCK5
  
Species: Gallus gallus
  
Chr. number: 23
Strand: -1
Band:
Gene start: 4226397
Gene end: 4237898
  
Corresponding Affymetrix probe sets: GgaAffx.11377.1.S1_s_at (Chicken Array)   GgaAffx.1501.7.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047611
Ensembl peptide - ENSGALP00000058495
Ensembl peptide - ENSGALP00000055151
NCBI entrez gene - 419629     See in Manteia.
RefSeq - NM_001039276
RefSeq Peptide - NP_001034365
swissprot - A0A1D5PZS8
swissprot - A0A1D5PQI6
swissprot - Q5ZMW0
Ensembl - ENSGALG00000039713
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ago4ENSDARG00000100854Danio rerio
 AGO4ENSG00000134698Homo sapiens
 Ago4ENSMUSG00000042500Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AGO1 / argonaute 1, RISC catalytic component / Q8CJG1* / Q9UL18* / Protein argonaute-1 *ENSGALG0000000224984
AGO3 / protein argonaute-3 / Q8CJF9* / Q9H9G7* / argonaute 3, RISC catalytic component*ENSGALG0000004371182
AGO2 / argonaute 2, RISC catalytic component / Q8CJG0* / Q9UKV8* / Protein argonaute-2 *ENSGALG0000004095777
A6N7Y9 / PIWIL1 / Piwi-like protein 1 / Q96J94* / Q9JMB7* / piwi like RNA-mediated gene silencing 1*ENSGALG0000000264522


Protein motifs (from Interpro)
Interpro ID Name
 IPR003100  PAZ domain
 IPR003165  Piwi domain
 IPR012337  Ribonuclease H-like superfamily
 IPR014811  Argonaute, linker 1 domain
 IPR028604  Protein argonaute-4
 IPR032472  Argonaute linker 2 domain
 IPR032473  Protein argonaute, Mid domain
 IPR032474  Protein argonaute, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006402 mRNA catabolic process IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0007130 synaptonemal complex assembly IEA
 biological_processGO:0007140 male meiotic nuclear division IEA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0010501 RNA secondary structure unwinding IEA
 biological_processGO:0010586 miRNA metabolic process IEA
 biological_processGO:0022604 regulation of cell morphogenesis IEA
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0031054 pre-miRNA processing IEA
 biological_processGO:0035196 production of miRNAs involved in gene silencing by miRNA IEA
 biological_processGO:0035278 miRNA mediated inhibition of translation IEA
 biological_processGO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 cellular_componentGO:0000932 P-body IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016442 RISC complex IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0035068 micro-ribonucleoprotein complex IEA
 cellular_componentGO:0070578 RISC-loading complex IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003725 double-stranded RNA binding IEA
 molecular_functionGO:0003727 single-stranded RNA binding IEA
 molecular_functionGO:0035198 miRNA binding IEA


Pathways (from Reactome)
Pathway description
MicroRNA (miRNA) biogenesis
Small interfering RNA (siRNA) biogenesis
Post-transcriptional silencing by small RNAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001558 MOV10 / putative helicase MOV-10 / P23249* / Q9HCE1* / Mov10 RISC complex RNA helicase*  / complex






 

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