ENSGALG00000044146


Gallus gallus

Features
Gene ID: ENSGALG00000044146
  
Biological name :PNP
  
Synonyms : PNP / purine nucleoside phosphorylase
  
Possible biological names infered from orthology : P00491 / Pnp2
  
Species: Gallus gallus
  
Chr. number: 11
Strand: -1
Band:
Gene start: 1554680
Gene end: 1560904
  
Corresponding Affymetrix probe sets: GgaAffx.1566.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000058946
NCBI entrez gene - 769958     See in Manteia.
RefSeq - XM_003641902
swissprot - A0A1L1RJM3
Ensembl - ENSGALG00000044146
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pnp6ENSDARG00000040942Danio rerio
 PNPENSG00000198805Homo sapiens
 PnpENSMUSG00000021871Mus musculus
 PnpENSMUSG00000115338Mus musculus
 Pnp2ENSMUSG00000068417Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000845  Nucleoside phosphorylase domain
 IPR011268  Purine nucleoside phosphorylase
 IPR011270  Purine nucleoside phosphorylase I, inosine/guanosine-specific


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006139 nucleobase-containing compound metabolic process IEA
 biological_processGO:0006148 inosine catabolic process IEA
 biological_processGO:0006738 nicotinamide riboside catabolic process IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0009116 nucleoside metabolic process IEA
 biological_processGO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway IEA
 biological_processGO:0034418 urate biosynthetic process IEA
 biological_processGO:0042102 positive regulation of T cell proliferation IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0046638 positive regulation of alpha-beta T cell differentiation IEA
 biological_processGO:0070970 interleukin-2 secretion IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0001882 nucleoside binding IEA
 molecular_functionGO:0002060 purine nucleobase binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004731 purine-nucleoside phosphorylase activity IEA
 molecular_functionGO:0008144 drug binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0042301 phosphate ion binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Purine salvage
Purine catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000044146 PNP / purine nucleoside phosphorylase / Pnp2* / P00491*  / complex






 

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