ENSMUSG00000068417


Mus musculus

Features
Gene ID: ENSMUSG00000068417
  
Biological name :Pnp2
  
Synonyms : Pnp2
  
Possible biological names infered from orthology : P00491 / PNP / purine nucleoside phosphorylase
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: C1
Gene start: 50955992
Gene end: 50964749
  
Corresponding Affymetrix probe sets: 10414527 (MoGene1.0st)   1453299_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000093615
NCBI entrez gene - 667034     See in Manteia.
MGI - MGI:3712328
RefSeq - NM_001123371
RefSeq - XM_011245151
RefSeq Peptide - NP_001116843
swissprot - Q9D8C9
Ensembl - ENSMUSG00000068417
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pnp5aENSDARG00000078619Danio rerio
 pnp5bENSDARG00000099802Danio rerio
 PNPENSGALG00000044146Gallus gallus
 PNPENSG00000198805Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pnp / P00491* / purine nucleoside phosphorylase*ENSMUSG0000011533891
Pnp / P00491* / purine nucleoside phosphorylase*ENSMUSG0000002187174


Protein motifs (from Interpro)
Interpro ID Name
 IPR000845  Nucleoside phosphorylase domain
 IPR011268  Purine nucleoside phosphorylase
 IPR011270  Purine nucleoside phosphorylase I, inosine/guanosine-specific
 IPR018099  Purine phosphorylase, family 2, conserved site
 IPR035994  Nucleoside phosphorylase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006139 nucleobase-containing compound metabolic process IEA
 biological_processGO:0009116 nucleoside metabolic process IEA
 cellular_componentGO:0005622 intracellular ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005829 cytosol ISO
 molecular_functionGO:0001882 nucleoside binding ISO
 molecular_functionGO:0002060 purine nucleobase binding ISO
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004731 purine-nucleoside phosphorylase activity IEA
 molecular_functionGO:0008144 drug binding ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0016763 transferase activity, transferring pentosyl groups IEA
 molecular_functionGO:0042301 phosphate ion binding ISO


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Purine salvage
Purine catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000115338 Pnp / P00491* / purine nucleoside phosphorylase*  / complex
 ENSMUSG00000068417 Pnp2 / PNP* / P00491* / purine nucleoside phosphorylase*  / complex






 

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