ENSGALG00000044442


Gallus gallus

Features
Gene ID: ENSGALG00000044442
  
Biological name :THBD
  
Synonyms : THBD / thrombomodulin
  
Possible biological names infered from orthology : P07204 / P15306
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 3336992
Gene end: 3338641
  
Corresponding Affymetrix probe sets: GgaAffx.5274.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000063331
NCBI entrez gene - 101752029     See in Manteia.
RefSeq - XM_004940137
swissprot - A0A1L1RWW5
Ensembl - ENSGALG00000044442
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 thbdENSDARG00000092470Danio rerio
 THBDENSG00000178726Homo sapiens
 ThbdENSMUSG00000074743Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CD93 / CD93 molecule / O89103* / Q9NPY3* / Complement component C1q receptor *ENSGALG0000000835927
SCUBE1 / signal peptide, CUB domain and EGF like domain containing 1 / Q6NZL8* / Q8IWY4* / signal peptide, CUB domain, EGF-like 1*ENSGALG0000001417822
SCUBE3 / signal peptide, CUB domain and EGF like domain containing 3 / Q66PY1* / Q8IX30* / Signal peptide, CUB and EGF-like domain-containing protein 3 *ENSGALG0000000267520
SCUBE2 / signal peptide, CUB domain and EGF like domain containing 2 / Q9JJS0* / Q9NQ36* / Signal peptide, CUB and EGF-like domain-containing protein 2 *ENSGALG0000003216120
MATN2 / matrilin 2 / O00339* / O08746* / Mus musculus matrilin 2 (Matn2), transcript variant 1, mRNA.*ENSGALG0000004467516
MATN4* / Q8VCP9* / O95460* / Q86T13* / CLEC14A* / matrilin 4* / C-type lectin domain containing 14A* / C-type lectin domain family 14 member A *ENSGALG0000000402814
MATN3 / O42401 / Matrilin-3 / O15232* / O35701*ENSGALG0000001647812
MATN1 / matrilin 1, cartilage matrix protein / P21941* / P51942* / Cartilage matrix protein *ENSGALG000000431858
VWA1 / von Willebrand factor A domain containing 1 / Q6PCB0* / Q8R2Z5*ENSGALG000000015273


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001304  C-type lectin-like
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR015149  Thrombomodulin-like, EGF-like
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR016316  Thrombomodulin
 IPR018097  EGF-like calcium-binding, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007565 female pregnancy IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Common Pathway of Fibrin Clot Formation
Cell surface interactions at the vascular wall


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008332 F2 / prothrombin precursor / P00734* / P19221* / coagulation factor II, thrombin* / Prothrombin Activation peptide fragment 1 Activation peptide fragment 2 Thrombin light chain Thrombin heavy chain*  / complex / reaction






 

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