ENSGALG00000002675


Gallus gallus

Features
Gene ID: ENSGALG00000002675
  
Biological name :SCUBE3
  
Synonyms : SCUBE3 / signal peptide, CUB domain and EGF like domain containing 3
  
Possible biological names infered from orthology : Q66PY1 / Q8IX30 / Signal peptide, CUB and EGF-like domain-containing protein 3
  
Species: Gallus gallus
  
Chr. number: 26
Strand: -1
Band:
Gene start: 4137688
Gene end: 4165193
  
Corresponding Affymetrix probe sets: Gga.15810.1.S1_at (Chicken Array)   GgaAffx.25579.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004206
NCBI entrez gene - 419896     See in Manteia.
RefSeq - XM_015299003
RefSeq - XM_015299004
RefSeq - XM_015299005
RefSeq - XM_418021
RefSeq - XM_004935034
swissprot - E1C8V3
Ensembl - ENSGALG00000002675
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 scube3ENSDARG00000011490Danio rerio
 Q8IX30ENSG00000146197Homo sapiens
 Q66PY1ENSMUSG00000038677Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SCUBE1 / signal peptide, CUB domain and EGF like domain containing 1 / Q6NZL8* / Q8IWY4* / signal peptide, CUB domain, EGF-like 1*ENSGALG0000001417870
SCUBE2 / signal peptide, CUB domain and EGF like domain containing 2 / Q9JJS0* / Q9NQ36* / Signal peptide, CUB and EGF-like domain-containing protein 2 *ENSGALG0000003216161
MATN2 / matrilin 2 / O00339* / O08746* / Mus musculus matrilin 2 (Matn2), transcript variant 1, mRNA.*ENSGALG0000004467513
CD93 / CD93 molecule / O89103* / Q9NPY3* / Complement component C1q receptor *ENSGALG0000000835912
THBD / thrombomodulin / P07204* / P15306*ENSGALG0000004444211
MATN4* / Q8VCP9* / O95460* / Q86T13* / CLEC14A* / matrilin 4* / C-type lectin domain containing 14A* / C-type lectin domain family 14 member A *ENSGALG0000000402810
MATN3 / O42401 / Matrilin-3 / O15232* / O35701*ENSGALG000000164787
MATN1 / matrilin 1, cartilage matrix protein / P21941* / P51942* / Cartilage matrix protein *ENSGALG000000431856
VWA1 / von Willebrand factor A domain containing 1 / Q6PCB0* / Q8R2Z5*ENSGALG000000015273


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR000859  CUB domain
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR011641  Tyrosine-protein kinase ephrin type A/B receptor-like
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site
 IPR024731  EGF domain
 IPR026823  Complement Clr-like EGF domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045880 positive regulation of smoothened signaling pathway IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0051291 protein heterooligomerization IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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