ENSMUSG00000002129


Mus musculus

Features
Gene ID: ENSMUSG00000002129
  
Biological name :Sf3a1
  
Synonyms : Q8K4Z5 / Sf3a1 / Splicing factor 3A subunit 1
  
Possible biological names infered from orthology : Q15459
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: A1
Gene start: 4160350
Gene end: 4182541
  
Corresponding Affymetrix probe sets: 10373873 (MoGene1.0st)   1419087_s_at (Mouse Genome 430 2.0 Array)   1445719_at (Mouse Genome 430 2.0 Array)   1446687_at (Mouse Genome 430 2.0 Array)   1449333_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000002198
NCBI entrez gene - 67465     See in Manteia.
MGI - MGI:1914715
RefSeq - NM_026175
RefSeq Peptide - NP_080451
swissprot - Q8K4Z5
Ensembl - ENSMUSG00000002129
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sf3a1ENSDARG00000041887Danio rerio
 SF3A1ENSGALG00000007937Gallus gallus
 SF3A1ENSG00000099995Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000061  SWAP/Surp
 IPR000626  Ubiquitin domain
 IPR022030  Splicing factor 3A subunit 1
 IPR029071  Ubiquitin-like domain superfamily
 IPR035563  Splicing factor 3A subunit 1, ubiquitin domain
 IPR035967  SWAP/Surp superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000381 regulation of alternative mRNA splicing, via spliceosome IBA
 biological_processGO:0000389 mRNA 3"-splice site recognition IBA
 biological_processGO:0000398 mRNA splicing, via spliceosome IEA
 biological_processGO:0006396 RNA processing IEA
 biological_processGO:0006397 mRNA processing ISO
 biological_processGO:0008380 RNA splicing IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005681 spliceosomal complex ISO
 cellular_componentGO:0005684 U2-type spliceosomal complex IEA
 cellular_componentGO:0005686 U2 snRNP IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0071004 U2-type prespliceosome IBA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IEA
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0006204 embryonic lethality before implantation "death anytime after fertilization but before implantation (E0 to less than E4.5)" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Hsp90aa1Tg(Tyr)2396BOve/Hsp90aa1Tg(Tyr)2396BOve
Genetic Background: FVB/N-Hsp90aa1Tg(Tyr)2396BOve

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000028902 Sf3a3 / Q9D554 / splicing factor 3a, subunit 3 / Q12874*  / complex
 ENSMUSG00000020211 Sf3a2 / splicing factor 3a, subunit 2 / Q15428*  / complex






 

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