ENSMUSG00000005124


Mus musculus

Features
Gene ID: ENSMUSG00000005124
  
Biological name :Wisp1
  
Synonyms : O54775 / Wisp1 / WNT1 inducible signaling pathway protein 1
  
Possible biological names infered from orthology : O95388
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: D2
Gene start: 66891320
Gene end: 66923201
  
Corresponding Affymetrix probe sets: 10424543 (MoGene1.0st)   1448593_at (Mouse Genome 430 2.0 Array)   1448594_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000113144
Ensembl peptide - ENSMUSP00000117402
Ensembl peptide - ENSMUSP00000005255
NCBI entrez gene - 22402     See in Manteia.
MGI - MGI:1197008
RefSeq - NM_018865
RefSeq - XM_006520889
RefSeq Peptide - NP_061353
swissprot - D3Z6X6
swissprot - O54775
swissprot - Q3UFJ5
swissprot - A0A0R4J1T7
Ensembl - ENSMUSG00000005124
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wisp1aENSDARG00000054331Danio rerio
 wisp1bENSDARG00000076685Danio rerio
 WISP1ENSGALG00000030115Gallus gallus
 WISP1ENSG00000104415Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Wisp3 / D3Z5L9 / WNT1 inducible signaling pathway protein 3 / O95389*ENSMUSG0000006207440
Ctgf / P29268 / Connective tissue growth factor / P29279*ENSMUSG0000001999740
Cyr61 / P18406 / Protein CYR61 / O00622* / cysteine rich angiogenic inducer 61*ENSMUSG0000002819537
Nov / Q64299 / nephroblastoma overexpressed / P48745*ENSMUSG0000003736236
Wisp2 / WNT1 inducible signaling pathway protein 2 / O76076*ENSMUSG0000002765627


Protein motifs (from Interpro)
Interpro ID Name
 IPR000867  Insulin-like growth factor-binding protein, IGFBP
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001007  VWFC domain
 IPR006207  Cystine knot, C-terminal
 IPR006208  Glycoprotein hormone subunit beta
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR012395  IGFBP-related, CNN
 IPR017891  Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site
 IPR036383  Thrombospondin type-1 (TSP1) repeat superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IEA
 biological_processGO:0007155 cell adhesion IBA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0060548 negative regulation of cell death IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0005178 integrin binding IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005520 insulin-like growth factor binding IEA
 molecular_functionGO:0008201 heparin binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Itgb1tm10.1Ref/Itgb1tm10.1Ref
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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