ENSMUSG00000006378


Mus musculus

Features
Gene ID: ENSMUSG00000006378
  
Biological name :Gcat
  
Synonyms : 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial / Gcat / O88986
  
Possible biological names infered from orthology : glycine C-acetyltransferase / O75600
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: E1
Gene start: 79030874
Gene end: 79038353
  
Corresponding Affymetrix probe sets: 10425211 (MoGene1.0st)   1417823_at (Mouse Genome 430 2.0 Array)   1417824_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000006544
Ensembl peptide - ENSMUSP00000155003
NCBI entrez gene - 26912     See in Manteia.
MGI - MGI:1349389
RefSeq - NM_013847
RefSeq Peptide - NP_038875
swissprot - O88986
Ensembl - ENSMUSG00000006378
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gcatENSDARG00000005643Danio rerio
 GCATENSGALG00000012312Gallus gallus
 GCATENSG00000100116Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gcat / O75600* / glycine C-acetyltransferase*ENSMUSG0000011637888
Alas2 / P08680 / 5-aminolevulinate synthase, erythroid-specific, mitochondrial / P22557* / 5-aminolevulinate synthase 2*ENSMUSG0000002527034
Alas1 / Q8VC19 / 5-aminolevulinate synthase, nonspecific, mitochondrial / P13196* / 5-aminolevulinate synthase 1*ENSMUSG0000003278631


Protein motifs (from Interpro)
Interpro ID Name
 IPR001917  Aminotransferase, class-II, pyridoxal-phosphate binding site
 IPR004839  Aminotransferase, class I/classII
 IPR011282  2-amino-3-ketobutyrate coenzyme A ligase
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006567 threonine catabolic process IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009058 biosynthetic process IEA
 biological_processGO:0019518 L-threonine catabolic process to glycine IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005743 mitochondrial inner membrane IDA
 cellular_componentGO:0016607 nuclear speck ISO
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0008890 glycine C-acetyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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