ENSMUSG00000011158


Mus musculus

Features
Gene ID: ENSMUSG00000011158
  
Biological name :Brf1
  
Synonyms : Brf1 / BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
  
Possible biological names infered from orthology : BRF1, RNA polymerase III transcription initiation factor subunit / Q92994
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: F1
Gene start: 112960085
Gene end: 113000704
  
Corresponding Affymetrix probe sets: 10402841 (MoGene1.0st)   1453209_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000011302
NCBI entrez gene - 72308     See in Manteia.
MGI - MGI:1919558
RefSeq - XM_017315211
RefSeq - NM_028193
RefSeq - XM_011244184
RefSeq - XM_011244185
RefSeq - XM_006516260
RefSeq - XM_006516261
RefSeq - XM_006516266
RefSeq - XM_006516267
RefSeq - XM_011244182
RefSeq - XM_011244183
RefSeq Peptide - NP_082469
swissprot - G3X8S2
Ensembl - ENSMUSG00000011158
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 brf1aENSDARG00000017835Danio rerio
 brf1bENSDARG00000005002Danio rerio
 BRF1ENSGALG00000011705Gallus gallus
 BRF1ENSG00000185024Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000812  Transcription factor TFIIB
 IPR011665  Brf1, TBP-binding domain
 IPR013137  Zinc finger, TFIIB-type
 IPR013150  Transcription factor TFIIB, cyclin-like domain
 IPR013763  Cyclin-like
 IPR029529  Transcription factor IIIB subunit Brf1
 IPR036915  Cyclin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006383 transcription by RNA polymerase III IEA
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0045945 positive regulation of transcription by RNA polymerase III IEA
 biological_processGO:0070897 DNA-templated transcriptional preinitiation complex assembly IEA
 cellular_componentGO:0000126 transcription factor TFIIIB complex IEA
 molecular_functionGO:0001026 obsolete TFIIIB-type transcription factor activity IEA
 molecular_functionGO:0003743 translation initiation factor activity IEA
 molecular_functionGO:0017025 TBP-class protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000014767 Tbp / P29037 / TATA box binding protein / P20226*  / complex
 ENSMUSG00000049658 Bdp1 / Q571C7 / Transcription factor TFIIIB component B homolog / A6H8Y1* / B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB*  / complex






 

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