ENSMUSG00000013921


Mus musculus

Features
Gene ID: ENSMUSG00000013921
  
Biological name :Clip3
  
Synonyms : B9EHT4 / CAP-Gly domain-containing linker protein 3 / Clip3
  
Possible biological names infered from orthology : AC006030.1
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B1
Gene start: 30291728
Gene end: 30308367
  
Corresponding Affymetrix probe sets: 10551852 (MoGene1.0st)   1430543_at (Mouse Genome 430 2.0 Array)   1435256_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000014065
Ensembl peptide - ENSMUSP00000123660
Ensembl peptide - ENSMUSP00000123164
Ensembl peptide - ENSMUSP00000121276
NCBI entrez gene - 76686     See in Manteia.
MGI - MGI:1923936
RefSeq - XM_006540411
RefSeq - NM_001081114
RefSeq - XM_006540410
RefSeq Peptide - NP_001074583
swissprot - D3Z115
swissprot - D3Z2W8
swissprot - D3YXY6
swissprot - B9EHT4
Ensembl - ENSMUSG00000013921
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 clip3ENSDARG00000054456Danio rerio
 AC006030.1ENSG00000264324Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Clip4 / Q8CI96 / CAP-Gly domain-containing linker protein 4 / Q8N3C7* / CAP-Gly domain containing linker protein family member 4*ENSMUSG0000002405954
Clip1 / Q922J3 / CAP-Gly domain-containing linker protein 1 / P30622*ENSMUSG0000004955019
Clip2 / Q9Z0H8 / CAP-Gly domain-containing linker protein 2 / Q9UDT6*ENSMUSG0000006314618
Cep350 / E9Q309 / Centrosome-associated protein 350 / Q5VT06* / centrosomal protein 350*ENSMUSG0000003367114
Tbcb / Q9D1E6 / Tubulin-folding cofactor B / Q99426*ENSMUSG0000000609510
Dctn1 / O08788 / Mus musculus dynactin 1 (Dctn1), transcript variant 4, mRNA. / Q14203* / dynactin subunit 1*ENSMUSG000000318659


Protein motifs (from Interpro)
Interpro ID Name
 IPR000938  CAP Gly-rich domain
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain
 IPR036770  Ankyrin repeat-containing domain superfamily
 IPR036859  CAP Gly-rich domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IDA
 biological_processGO:0010828 positive regulation of glucose transmembrane transport IMP
 biological_processGO:0018230 peptidyl-L-cysteine S-palmitoylation ISO
 biological_processGO:0031115 negative regulation of microtubule polymerization ISO
 biological_processGO:0043065 positive regulation of apoptotic process ISS
 biological_processGO:0044091 membrane biogenesis ISO
 biological_processGO:0045444 fat cell differentiation IEP
 biological_processGO:0045807 positive regulation of endocytosis ISO
 biological_processGO:0072321 chaperone-mediated protein transport ISO
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005795 Golgi stack IEA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031901 early endosome membrane ISS
 cellular_componentGO:0032588 trans-Golgi network membrane ISS
 cellular_componentGO:0045121 membrane raft ISO
 cellular_componentGO:0055038 recycling endosome membrane ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding ISO
 molecular_functionGO:0035594 ganglioside binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000738 impaired muscle contractility "inability or reduced ability of a muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Fostm1.1(cre/ERT2)Luo/Fos+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001052 abnormal muscle innervation "malfomation or misprojection of sensory or motor nerves to targets in muscle" [J:75958]
Show

Allelic Composition: Fostm1.1(cre/ERT2)Luo/Fos+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001053 abnormal neuromuscular synapse "malformed or absent membrane to membrane contact of a motor axon and a muscle myofiber resulting in aberrant transmission of nerve impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159, J:47439]
Show

Allelic Composition: Fostm1.1(cre/ERT2)Luo/Fos+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001078 abnormal phrenic nerve "malformed or misprojection of motor and sensory neuron axons to the diaphragm and other tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
Show

Allelic Composition: Fostm1.1(cre/ERT2)Luo/Fos+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001575 cyanosis "a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159]
Show

Allelic Composition: Fostm1.1(cre/ERT2)Luo/Fos+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001953 respiratory failure "cessation of or failure to commence breathing" [MGI:cls, J:60159]
Show

Allelic Composition: Fostm1.1(cre/ERT2)Luo/Fos+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0002279 abnormal diaphragm morphology "structural defect in the thin musculomebraneous barrier that separates the abdominal and thoracic cavities; these muscles often used for breathing control" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Fostm1.1(cre/ERT2)Luo/Fos+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Fostm1.1(cre/ERT2)Luo/Fos+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0012055 abnormal phrenic nerve innervation pattern to diaphragm "any changes in the placement, morphology or number of the portion of phrenic nerve fibers providing motor supply to the diaphragm" [MGI:csmith]
Show

Allelic Composition: Fostm1.1(cre/ERT2)Luo/Fos+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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