ENSMUSG00000014195


Mus musculus

Features
Gene ID: ENSMUSG00000014195
  
Biological name :Dnajc7
  
Synonyms : Dnajc7 / DnaJ homolog subfamily C member 7 / Q9QYI3
  
Possible biological names infered from orthology : DnaJ heat shock protein family (Hsp40) member C7 / Q99615
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: D
Gene start: 100582818
Gene end: 100620168
  
Corresponding Affymetrix probe sets: 10391178 (MoGene1.0st)   1448362_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000014339
Ensembl peptide - ENSMUSP00000115438
Ensembl peptide - ENSMUSP00000116793
NCBI entrez gene - 56354     See in Manteia.
MGI - MGI:1928373
RefSeq - XM_011249154
RefSeq - NM_019795
RefSeq Peptide - NP_062769
swissprot - A2A5E1
swissprot - Q9QYI3
swissprot - F7BTP8
Ensembl - ENSMUSG00000014195
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dnajc7ENSDARG00000058148Danio rerio
 DNAJC7ENSGALG00000042796Gallus gallus
 DNAJC7ENSG00000168259Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dnajc3 / Q91YW3 / DnaJ homolog subfamily C member 3 / Q13217* / DnaJ heat shock protein family (Hsp40) member C3*ENSMUSG0000002213626


Protein motifs (from Interpro)
Interpro ID Name
 IPR001623  DnaJ domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR013105  Tetratricopeptide repeat 2
 IPR019734  Tetratricopeptide repeat
 IPR036869  Chaperone J-domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0051085 chaperone cofactor-dependent protein refolding IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0031072 heat shock protein binding IEA


Pathways (from Reactome)
Pathway description
Regulation of HSF1-mediated heat shock response


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002628 fatty liver "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Kif1algdg/Kif1algdg
Genetic Background: C3.Cg-Kif1algdg/GrsrJ

 MP:0003960 increased lean body mass "more than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
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Allelic Composition: Diaph3tm1b(KOMP)Mbp/Diaph3tm1b(KOMP)Mbp
Genetic Background: C57BL/6N-Diaph3tm1b(KOMP)Mbp/J

 MP:0005178 increased total circulating cholesterol level "greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Kif1algdg/Kif1algdg
Genetic Background: C3.Cg-Kif1algdg/GrsrJ

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Diaph3tm1b(KOMP)Mbp/Diaph3tm1b(KOMP)Mbp
Genetic Background: C57BL/6N-Diaph3tm1b(KOMP)Mbp/J

 MP:0011275 abnormal behavioral response to light "unexpected change in the activity of an organism (in terms of movement, outward responses) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light" [GO:0009416, MGI:llw2]
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Allelic Composition: Diaph3tm1b(KOMP)Mbp/Diaph3tm1b(KOMP)Mbp
Genetic Background: C57BL/6N-Diaph3tm1b(KOMP)Mbp/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000091971 Q61696 / Hspa1a / Heat shock 70 kDa protein 1A / HSPA1B* / P0DMV8* / P0DMV9* / heat shock protein family A (Hsp70) member 1B* / heat shock protein family A (Hsp70) member 1A*  / reaction
 ENSMUSG00000062797 Q9DD02 / Hikeshi / Protein Hikeshi / Q53FT3* / Hikeshi, heat shock protein nuclear import factor*  / reaction
 ENSMUSG00000090877 P17879 / Hspa1b / Heat shock 70 kDa protein 1B / HSPA1A* / P0DMV8* / P0DMV9* / heat shock protein family A (Hsp70) member 1B* / heat shock protein family A (Hsp70) member 1A*  / reaction






 

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