ENSMUSG00000062797


Mus musculus

Features
Gene ID: ENSMUSG00000062797
  
Biological name :Hikeshi
  
Synonyms : Hikeshi / Protein Hikeshi / Q9DD02
  
Possible biological names infered from orthology : Hikeshi, heat shock protein nuclear import factor / Q53FT3
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: D3
Gene start: 89917529
Gene end: 89941204
  
Corresponding Affymetrix probe sets: 10565479 (MoGene1.0st)   1419351_a_at (Mouse Genome 430 2.0 Array)   1419352_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000112750
Ensembl peptide - ENSMUSP00000119806
Ensembl peptide - ENSMUSP00000147050
Ensembl peptide - ENSMUSP00000147023
Ensembl peptide - ENSMUSP00000146855
Ensembl peptide - ENSMUSP00000077951
Ensembl peptide - ENSMUSP00000102856
NCBI entrez gene - 67669     See in Manteia.
MGI - MGI:96738
RefSeq - XM_006508133
RefSeq - NM_001291286
RefSeq - NM_001291287
RefSeq - NM_001291288
RefSeq - NM_001291289
RefSeq - NM_026304
RefSeq - XM_006508132
RefSeq Peptide - NP_080580
RefSeq Peptide - NP_001278215
RefSeq Peptide - NP_001278216
RefSeq Peptide - NP_001278217
RefSeq Peptide - NP_001278218
swissprot - A0A140LJ25
swissprot - A0A140LIZ9
swissprot - Q9DD02
swissprot - D3YU13
swissprot - G5E8I4
swissprot - A0A140LIK3
Ensembl - ENSMUSG00000062797
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q568T4ENSDARG00000104071Danio rerio
 Q5ZK09ENSGALG00000001823Gallus gallus
 Q53FT3ENSG00000149196Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008493  Domain of unknown function DUF775
 IPR031318  OPI10 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006606 protein import into nucleus ISS
 biological_processGO:0007030 Golgi organization IMP
 biological_processGO:0015031 protein transport ISO
 biological_processGO:0030324 lung development IMP
 biological_processGO:0034605 cellular response to heat ISS
 cellular_componentGO:0005622 intracellular ISS
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISS
 molecular_functionGO:0008565 protein transporter activity ISO
 molecular_functionGO:0030544 Hsp70 protein binding ISS


Pathways (from Reactome)
Pathway description
Regulation of HSF1-mediated heat shock response


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001176 abnormal lung development "malformation or arrest of differentiation of the organs of respiration" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]
Show

Allelic Composition: Tenm4l7Rn3-6R/Tenm4l7Rn3-6R
Genetic Background: involves: BALB/cRl * C3H/Rl * C57BL/10Rl

 MP:0001575 cyanosis "a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159]
Show

Allelic Composition: Tenm4l7Rn3-6R/Tenm4l7Rn3-6R
Genetic Background: involves: BALB/cRl * C3H/Rl * C57BL/10Rl

 MP:0001958 emphysema "lung disease characterized by increased size of terminal bronchioles with destructive changes in their walls and reduction in number" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33629]
Show

Allelic Composition: Tenm4l7Rn3-6R/Tenm4l7Rn3-6R
Genetic Background: involves: BALB/cRl * C3H/Rl * C57BL/10Rl

 MP:0010809 abnormal Clara cell morphology "any structural anomaly of the rounded, club-shaped, nonciliated cell protruding between ciliated cells in bronchiolar epithelium, believed to be secretory in function" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Tenm4l7Rn3-6R/Tenm4l7Rn3-6R
Genetic Background: involves: BALB/cRl * C3H/Rl * C57BL/10Rl

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Tenm4l7Rn3-6R/Tenm4l7Rn3-6R
Genetic Background: involves: BALB/cRl * C3H/Rl * C57BL/10Rl

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Tenm4l7Rn3-6R/Tenm4l7Rn3-6R
Genetic Background: involves: BALB/cRl * C3H/Rl * C57BL/10Rl

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Tenm4l7Rn3-6R/Tenm4l7Rn3-6R
Genetic Background: involves: BALB/cRl * C3H/Rl * C57BL/10Rl

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000005483 Dnajb1 / Q9QYJ3 / DnaJ homolog subfamily B member 1 / P25685* / DnaJ heat shock protein family (Hsp40) member B1*  / reaction
 ENSMUSG00000014195 Dnajc7 / Q9QYI3 / DnaJ homolog subfamily C member 7 / Q99615* / DnaJ heat shock protein family (Hsp40) member C7*  / reaction
 ENSMUSG00000029014 Dnajc2 / P54103 / DnaJ homolog subfamily C member 2 / Q99543* / DnaJ heat shock protein family (Hsp40) member C2*  / reaction
 ENSMUSG00000091971 Q61696 / Hspa1a / Heat shock 70 kDa protein 1A / HSPA1B* / P0DMV8* / P0DMV9* / heat shock protein family A (Hsp70) member 1B* / heat shock protein family A (Hsp70) member 1A*  / complex / reaction
 ENSMUSG00000090877 P17879 / Hspa1b / Heat shock 70 kDa protein 1B / HSPA1A* / P0DMV8* / P0DMV9* / heat shock protein family A (Hsp70) member 1B* / heat shock protein family A (Hsp70) member 1A*  / reaction / complex






 

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