ENSMUSG00000015214


Mus musculus

Features
Gene ID: ENSMUSG00000015214
  
Biological name :Mtmr1
  
Synonyms : Mtmr1 / Myotubularin-related protein 1 / Q9Z2C4
  
Possible biological names infered from orthology : Q13613
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: A7.3
Gene start: 71364760
Gene end: 71419196
  
Corresponding Affymetrix probe sets: 10599997 (MoGene1.0st)   1421879_at (Mouse Genome 430 2.0 Array)   1421880_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000123363
Ensembl peptide - ENSMUSP00000015358
Ensembl peptide - ENSMUSP00000110248
Ensembl peptide - ENSMUSP00000115458
Ensembl peptide - ENSMUSP00000117342
Ensembl peptide - ENSMUSP00000121165
Ensembl peptide - ENSMUSP00000121342
NCBI entrez gene - 53332     See in Manteia.
MGI - MGI:1858271
RefSeq - XM_011247629
RefSeq - NM_001313702
RefSeq - NM_001313703
RefSeq - NM_001313704
RefSeq - NM_001313706
RefSeq - NM_001313707
RefSeq - NM_016985
RefSeq - XM_006528136
RefSeq - XM_006528137
RefSeq Peptide - NP_058681
RefSeq Peptide - NP_001300635
RefSeq Peptide - NP_001300636
RefSeq Peptide - NP_001300632
RefSeq Peptide - NP_001300633
RefSeq Peptide - NP_001300631
swissprot - Q9Z2C4
swissprot - F6T9H9
swissprot - I7HPV7
swissprot - I7HJQ9
swissprot - Q8CIU3
swissprot - Q8CIU5
swissprot - Q8CIU6
Ensembl - ENSMUSG00000015214
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mtmr1aENSDARG00000056690Danio rerio
 mtmr1bENSDARG00000022378Danio rerio
 MTMR1ENSGALG00000009085Gallus gallus
 MTMR1ENSG00000063601Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mtmr2 / Q9Z2D1 / Myotubularin-related protein 2 / Q13614*ENSMUSG0000003191865
Mtm1 / Q9Z2C5 / X-linked myotubular myopathy gene 1 / Q13496* / myotubularin 1*ENSMUSG0000003133752
Mtmr6 / Q8VE11 / Myotubularin-related protein 6 / Q9Y217*ENSMUSG0000002198731
Mtmr7 / Q9Z2C9 / Myotubularin-related protein 7 / Q9Y216*ENSMUSG0000003943131
Sbf1 / Q6ZPE2 / SET binding factor 1 / O95248*ENSMUSG0000003652929
Mtmr3 / myotubularin related protein 3 / Q13615*ENSMUSG0000003435429
Mtmr4 / Q91XS1 / Mus musculus myotubularin related protein 4 (Mtmr4), transcript variant 2, mRNA. / Q9NYA4* / myotubularin related protein 4*ENSMUSG0000001840128
Mtmr9 / Q9Z2D0 / Myotubularin-related protein 9 / Q96QG7*ENSMUSG0000003507828
Sbf2 / SET binding factor 2 / Q86WG5*ENSMUSG0000003837126


Protein motifs (from Interpro)
Interpro ID Name
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR004182  GRAM domain
 IPR010569  Myotubularin-like phosphatase domain
 IPR011993  PH-like domain superfamily
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like
 IPR030564  Myotubularin family
 IPR030587  Myotubularin-related protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0046856 phosphatidylinositol dephosphorylation ISO
 biological_processGO:0060304 regulation of phosphatidylinositol dephosphorylation ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004438 phosphatidylinositol-3-phosphatase activity ISO
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity ISO
 molecular_functionGO:0052866 phosphatidylinositol phosphate phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Icam1tm1Bay/Icam1tm1Bay,Selptm1Bay/Selptm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Mtmr1tm1Dgen/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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