ENSG00000063601


Homo sapiens

Features
Gene ID: ENSG00000063601
  
Biological name :MTMR1
  
Synonyms : MTMR1 / myotubularin related protein 1 / Q13613
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: q28
Gene start: 150692971
Gene end: 150765103
  
Corresponding Affymetrix probe sets: 213511_s_at (Human Genome U133 Plus 2.0 Array)   214975_s_at (Human Genome U133 Plus 2.0 Array)   216095_x_at (Human Genome U133 Plus 2.0 Array)   216303_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000434514
Ensembl peptide - ENSP00000434105
Ensembl peptide - ENSP00000436957
Ensembl peptide - ENSP00000445281
Ensembl peptide - ENSP00000359417
Ensembl peptide - ENSP00000389884
Ensembl peptide - ENSP00000390736
Ensembl peptide - ENSP00000404599
Ensembl peptide - ENSP00000405946
Ensembl peptide - ENSP00000414178
Ensembl peptide - ENSP00000414925
Ensembl peptide - ENSP00000431992
NCBI entrez gene - 8776     See in Manteia.
OMIM - 300171
RefSeq - XM_017029924
RefSeq - NM_001306144
RefSeq - NM_001306145
RefSeq - NM_001353991
RefSeq - NM_001353992
RefSeq - NM_001353993
RefSeq - NM_001353994
RefSeq - NM_001353995
RefSeq - NM_001353996
RefSeq - NM_003828
RefSeq - XM_005274765
RefSeq - XM_005274766
RefSeq - XM_005274767
RefSeq - XM_006724855
RefSeq - XM_011531209
RefSeq - XM_011531210
RefSeq - XM_017029920
RefSeq - XM_017029921
RefSeq - XM_017029922
RefSeq - XM_017029923
RefSeq Peptide - NP_001340920
RefSeq Peptide - NP_001340921
RefSeq Peptide - NP_001340922
RefSeq Peptide - NP_001340923
RefSeq Peptide - NP_001340924
RefSeq Peptide - NP_001340925
RefSeq Peptide - NP_003819
RefSeq Peptide - NP_001293073
RefSeq Peptide - NP_001293074
swissprot - Q13613
swissprot - Q8NEC6
swissprot - F8W764
swissprot - F8W8S8
swissprot - F8WA39
swissprot - H0YDX3
swissprot - H7BZJ1
swissprot - H7C406
swissprot - E9PIH9
swissprot - E9PPP8
Ensembl - ENSG00000063601
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mtmr1aENSDARG00000056690Danio rerio
 mtmr1bENSDARG00000022378Danio rerio
 MTMR1ENSGALG00000009085Gallus gallus
 Mtmr1ENSMUSG00000015214Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MTMR2 / Q13614 / myotubularin related protein 2ENSG0000008705366
MTM1 / Q13496 / myotubularin 1ENSG0000017110052
MTMR6 / Q9Y217 / myotubularin related protein 6ENSG0000013950531
MTMR8 / Q96EF0 / myotubularin related protein 8ENSG0000010204330
MTMR3 / Q13615 / myotubularin related protein 3ENSG0000010033030
MTMR7 / Q9Y216 / myotubularin related protein 7ENSG0000000398730
SBF1 / O95248 / SET binding factor 1ENSG0000010024129
MTMR9 / Q96QG7 / myotubularin related protein 9ENSG0000010464328
MTMR4 / Q9NYA4 / myotubularin related protein 4ENSG0000010838928
SBF2 / Q86WG5 / SET binding factor 2ENSG0000013381227


Protein motifs (from Interpro)
Interpro ID Name
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR004182  GRAM domain
 IPR010569  Myotubularin-like phosphatase domain
 IPR011993  PH-like domain superfamily
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like
 IPR030564  Myotubularin family
 IPR030587  Myotubularin-related protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006661 phosphatidylinositol biosynthetic process TAS
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0046856 phosphatidylinositol dephosphorylation IEA
 biological_processGO:0060304 regulation of phosphatidylinositol dephosphorylation IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004438 phosphatidylinositol-3-phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity IEA
 molecular_functionGO:0052866 phosphatidylinositol phosphate phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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