ENSG00000104643


Homo sapiens

Features
Gene ID: ENSG00000104643
  
Biological name :MTMR9
  
Synonyms : MTMR9 / myotubularin related protein 9 / Q96QG7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: p23.1
Gene start: 11284416
Gene end: 11328146
  
Corresponding Affymetrix probe sets: 204837_at (Human Genome U133 Plus 2.0 Array)   213278_at (Human Genome U133 Plus 2.0 Array)   233101_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000433239
Ensembl peptide - ENSP00000436046
Ensembl peptide - ENSP00000221086
NCBI entrez gene - 66036     See in Manteia.
OMIM - 606260
RefSeq - NM_015458
RefSeq - XM_011543830
RefSeq - XM_011543831
RefSeq Peptide - NP_056273
swissprot - E9PR67
swissprot - Q96QG7
Ensembl - ENSG00000104643
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mtmr9ENSDARG00000015860Danio rerio
 MTMR9ENSGALG00000016649Gallus gallus
 Mtmr9ENSMUSG00000035078Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MTMR7 / Q9Y216 / myotubularin related protein 7ENSG0000000398736
MTMR2 / Q13614 / myotubularin related protein 2ENSG0000008705335
MTMR1 / Q13613 / myotubularin related protein 1ENSG0000006360134
MTMR6 / Q9Y217 / myotubularin related protein 6ENSG0000013950534
MTMR8 / Q96EF0 / myotubularin related protein 8ENSG0000010204333
MTM1 / Q13496 / myotubularin 1ENSG0000017110032
MTMR3 / Q13615 / myotubularin related protein 3ENSG0000010033030
MTMR4 / Q9NYA4 / myotubularin related protein 4ENSG0000010838930
SBF1 / O95248 / SET binding factor 1ENSG0000010024128
SBF2 / Q86WG5 / SET binding factor 2ENSG0000013381225


Protein motifs (from Interpro)
Interpro ID Name
 IPR010569  Myotubularin-like phosphatase domain
 IPR011993  PH-like domain superfamily
 IPR029021  Protein-tyrosine phosphatase-like
 IPR030564  Myotubularin family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006661 phosphatidylinositol biosynthetic process TAS
 biological_processGO:0010507 negative regulation of autophagy IPI
 biological_processGO:0010922 positive regulation of phosphatase activity IDA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0050821 protein stabilization IDA
 biological_processGO:0060304 regulation of phosphatidylinositol dephosphorylation IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0004438 phosphatidylinositol-3-phosphatase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019903 protein phosphatase binding IPI
 molecular_functionGO:0030234 enzyme regulator activity IEA
 molecular_functionGO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity TAS


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane
Synthesis of PIPs at the late endosome membrane
Synthesis of IP2, IP, and Ins in the cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000003987 MTMR7 / Q9Y216 / myotubularin related protein 7  / reaction / complex
 ENSG00000102043 MTMR8 / Q96EF0 / myotubularin related protein 8  / reaction / complex
 ENSG00000139505 MTMR6 / Q9Y217 / myotubularin related protein 6  / reaction / complex






 

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