ENSG00000100330


Homo sapiens

Features
Gene ID: ENSG00000100330
  
Biological name :MTMR3
  
Synonyms : MTMR3 / myotubularin related protein 3 / Q13615
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q12.2
Gene start: 29883155
Gene end: 30030866
  
Corresponding Affymetrix probe sets: 202197_at (Human Genome U133 Plus 2.0 Array)   202198_s_at (Human Genome U133 Plus 2.0 Array)   211507_s_at (Human Genome U133 Plus 2.0 Array)   226956_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000384077
Ensembl peptide - ENSP00000331649
Ensembl peptide - ENSP00000384651
Ensembl peptide - ENSP00000409063
Ensembl peptide - ENSP00000307271
Ensembl peptide - ENSP00000318070
NCBI entrez gene - 8897     See in Manteia.
OMIM - 603558
RefSeq - XM_017029034
RefSeq - XM_005261808
RefSeq - XM_017029028
RefSeq - XM_017029029
RefSeq - XM_017029030
RefSeq - XM_017029031
RefSeq - XM_017029032
RefSeq - XM_017029033
RefSeq - NM_021090
RefSeq - NM_153050
RefSeq - NM_153051
RefSeq - XM_005261803
RefSeq - XM_005261804
RefSeq - XM_005261805
RefSeq - XM_005261806
RefSeq Peptide - NP_694691
RefSeq Peptide - NP_066576
RefSeq Peptide - NP_694690
swissprot - A0A024R1I2
swissprot - Q13615
swissprot - G5E953
swissprot - C9JLU3
Ensembl - ENSG00000100330
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mtmr3ENSDARG00000098201Danio rerio
 mtmr3ENSDARG00000093364Danio rerio
 MTMR3ENSGALG00000008051Gallus gallus
 Mtmr3ENSMUSG00000034354Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MTMR4 / Q9NYA4 / myotubularin related protein 4ENSG0000010838949
MTMR2 / Q13614 / myotubularin related protein 2ENSG0000008705319
SBF1 / O95248 / SET binding factor 1ENSG0000010024118
MTMR6 / Q9Y217 / myotubularin related protein 6ENSG0000013950518
MTMR8 / Q96EF0 / myotubularin related protein 8ENSG0000010204317
MTMR7 / Q9Y216 / myotubularin related protein 7ENSG0000000398717
MTM1 / Q13496 / myotubularin 1ENSG0000017110017
MTMR1 / Q13613 / myotubularin related protein 1ENSG0000006360117
SBF2 / Q86WG5 / SET binding factor 2ENSG0000013381216
MTMR9 / Q96QG7 / myotubularin related protein 9ENSG0000010464314


Protein motifs (from Interpro)
Interpro ID Name
 IPR000306  FYVE zinc finger
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR010569  Myotubularin-like phosphatase domain
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR011993  PH-like domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR017455  Zinc finger, FYVE-related
 IPR029021  Protein-tyrosine phosphatase-like
 IPR030564  Myotubularin family
 IPR035888  Myotubularin-related protein 3, PH-GRAM domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IDA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006661 phosphatidylinositol biosynthetic process TAS
 biological_processGO:0016236 macroautophagy TAS
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0042149 cellular response to glucose starvation IMP
 biological_processGO:0046856 phosphatidylinositol dephosphorylation IDA
 biological_processGO:0060304 regulation of phosphatidylinositol dephosphorylation IDA
 biological_processGO:1904562 phosphatidylinositol 5-phosphate metabolic process IDA
 biological_processGO:2000785 regulation of autophagosome assembly IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0019898 extrinsic component of membrane IDA
 molecular_functionGO:0004438 phosphatidylinositol-3-phosphatase activity IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IDA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019903 protein phosphatase binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity IDA


Pathways (from Reactome)
Pathway description
Macroautophagy
Synthesis of PIPs at the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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