ENSG00000102043


Homo sapiens

Features
Gene ID: ENSG00000102043
  
Biological name :MTMR8
  
Synonyms : MTMR8 / myotubularin related protein 8 / Q96EF0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: q11.2
Gene start: 64268081
Gene end: 64395431
  
Corresponding Affymetrix probe sets: 220537_at (Human Genome U133 Plus 2.0 Array)   221390_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000363985
NCBI entrez gene - 55613     See in Manteia.
RefSeq - NM_017677
RefSeq Peptide - NP_060147
swissprot - Q96EF0
Ensembl - ENSG00000102043
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mtmr8ENSDARG00000008592Danio rerio
 MTMR8ENSGALG00000007590Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MTMR6 / Q9Y217 / myotubularin related protein 6ENSG0000013950550
MTMR7 / Q9Y216 / myotubularin related protein 7ENSG0000000398749
MTMR2 / Q13614 / myotubularin related protein 2ENSG0000008705330
MTM1 / Q13496 / myotubularin 1ENSG0000017110030
MTMR3 / Q13615 / myotubularin related protein 3ENSG0000010033029
MTMR1 / Q13613 / myotubularin related protein 1ENSG0000006360129
MTMR4 / Q9NYA4 / myotubularin related protein 4ENSG0000010838929
MTMR9 / Q96QG7 / myotubularin related protein 9ENSG0000010464326
SBF2 / Q86WG5 / SET binding factor 2ENSG0000013381222
SBF1 / O95248 / SET binding factor 1ENSG0000010024122


Protein motifs (from Interpro)
Interpro ID Name
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR010569  Myotubularin-like phosphatase domain
 IPR011993  PH-like domain superfamily
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like
 IPR030564  Myotubularin family
 IPR030591  Myotubularin-related protein 8


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006661 phosphatidylinositol biosynthetic process TAS
 biological_processGO:0010506 regulation of autophagy IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0046856 phosphatidylinositol dephosphorylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004438 phosphatidylinositol-3-phosphatase activity TAS
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity TAS


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000104643 MTMR9 / Q96QG7 / myotubularin related protein 9  / reaction / complex






 

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