ENSMUSG00000021987


Mus musculus

Features
Gene ID: ENSMUSG00000021987
  
Biological name :Mtmr6
  
Synonyms : Mtmr6 / Myotubularin-related protein 6 / Q8VE11
  
Possible biological names infered from orthology : Q9Y217
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: D1
Gene start: 60265228
Gene end: 60302370
  
Corresponding Affymetrix probe sets: 10415700 (MoGene1.0st)   1425485_at (Mouse Genome 430 2.0 Array)   1425486_s_at (Mouse Genome 430 2.0 Array)   1451726_at (Mouse Genome 430 2.0 Array)   1456540_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022563
Ensembl peptide - ENSMUSP00000153403
NCBI entrez gene - 219135     See in Manteia.
MGI - MGI:2145637
RefSeq - XM_017315972
RefSeq - NM_144843
RefSeq - XM_006518865
RefSeq - XM_017315971
RefSeq Peptide - NP_659092
swissprot - L8AZD2
swissprot - Q8VE11
Ensembl - ENSMUSG00000021987
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mtmr6ENSDARG00000016794Danio rerio
 MTMR6ENSGALG00000017112Gallus gallus
 MTMR6ENSG00000139505Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mtmr7 / Q9Z2C9 / Myotubularin-related protein 7 / Q9Y216*ENSMUSG0000003943159
Mtmr2 / Q9Z2D1 / Myotubularin-related protein 2 / Q13614*ENSMUSG0000003191835
Mtm1 / Q9Z2C5 / X-linked myotubular myopathy gene 1 / Q13496* / myotubularin 1*ENSMUSG0000003133734
Mtmr3 / myotubularin related protein 3 / Q13615*ENSMUSG0000003435434
Mtmr1 / Q9Z2C4 / Myotubularin-related protein 1 / Q13613*ENSMUSG0000001521434
Mtmr4 / Q91XS1 / Mus musculus myotubularin related protein 4 (Mtmr4), transcript variant 2, mRNA. / Q9NYA4* / myotubularin related protein 4*ENSMUSG0000001840134
Mtmr9 / Q9Z2D0 / Myotubularin-related protein 9 / Q96QG7*ENSMUSG0000003507830
Sbf1 / Q6ZPE2 / SET binding factor 1 / O95248*ENSMUSG0000003652926
Sbf2 / SET binding factor 2 / Q86WG5*ENSMUSG0000003837124


Protein motifs (from Interpro)
Interpro ID Name
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR010569  Myotubularin-like phosphatase domain
 IPR011993  PH-like domain superfamily
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like
 IPR030564  Myotubularin family
 IPR030581  Myotubularin-related protein 6
 IPR035998  MTMR6, PH-GRAM domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0046856 phosphatidylinositol dephosphorylation IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004438 phosphatidylinositol-3-phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0015269 calcium-activated potassium channel activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0052866 phosphatidylinositol phosphate phosphatase activity IEA
 molecular_functionGO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000035078 Mtmr9 / Q9Z2D0 / Myotubularin-related protein 9 / Q96QG7*  / reaction / complex






 

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