ENSMUSG00000015365


Mus musculus

Features
Gene ID: ENSMUSG00000015365
  
Biological name :Mov10l1
  
Synonyms : Mov10l1 / Mov10 RISC complex RNA helicase like 1
  
Possible biological names infered from orthology : Q9BXT6
  
Species: Mus musculus
  
Chr. number: 15
Strand: 1
Band: E3
Gene start: 88982909
Gene end: 89055152
  
Corresponding Affymetrix probe sets: 10426118 (MoGene1.0st)   1419340_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000134200
Ensembl peptide - ENSMUSP00000015509
Ensembl peptide - ENSMUSP00000118437
NCBI entrez gene - 83456     See in Manteia.
MGI - MGI:1891384
RefSeq - XM_006521555
RefSeq - XM_006521558
RefSeq - XM_006521557
RefSeq - NM_031260
RefSeq - XM_006521556
RefSeq Peptide - NP_112550
swissprot - G3UYS5
swissprot - D3YWG8
swissprot - G3X8T0
Ensembl - ENSMUSG00000015365
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MOV10L1ENSGALG00000033664Gallus gallus
 Q9BXT6ENSG00000073146Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mov10 / P23249 / Putative helicase MOV-10 / Q9HCE1* / Mov10 RISC complex RNA helicase*ENSMUSG0000000222727
Helz / Q6DFV5 / Probable helicase with zinc finger domain / P42694* / helicase with zinc finger*ENSMUSG0000002072117
Helz2 / E9QAM5 / Helicase with zinc finger domain 2 / Q9BYK8* / helicase with zinc finger 2*ENSMUSG0000002758016
Upf1 / Q9EPU0 / UPF1 regulator of nonsense transcripts homolog (yeast) / Q92900* / UPF1, RNA helicase and ATPase*ENSMUSG0000005830115


Protein motifs (from Interpro)
Interpro ID Name
 IPR013783  Immunoglobulin-like fold
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007281 germ cell development IEA
 biological_processGO:0007283 spermatogenesis IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS

 MP:0001153 small seminiferous tubules "reduced diameter of the tubules in the testes where spermatogenesis occurs" [J:50844]
Show

Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS

 MP:0001154 seminiferous tubule degeneration "a retrogressive impairment of function or destruction of the tubules in the testes where spermatogenesis occurs" [J:50844]
Show

Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS

Allelic Composition: Mov10l1tm1.2Jw/Mov10l1tm1.2Jw
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0003698 abnormal male reproductive system physiology "anomaly in the function of the male organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS

Allelic Composition: Mov10l1tm1.2Jw/Mov10l1tm1.2Jw
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS

Allelic Composition: Mov10l1tm1.2Jw/Mov10l1tm1.2Jw
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS

Allelic Composition: Mov10l1tm1.2Jw/Mov10l1tm1.2Jw
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0005169 abnormal male meiosis "malfunction in the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS

Allelic Composition: Mov10l1tm1.2Jw/Mov10l1tm1.2Jw
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0006379 abnormal spermatocyte morphology "anomaly in the number or structure of male germ cells that through meiosis give rise to spermatids " [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS

 MP:0006380 abnormal spermatid morphology "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS

Allelic Composition: Mov10l1tm1.2Jw/Mov10l1tm1.2Jw
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0008280 male germ cell apoptosis "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: T/tbtm
Genetic Background: involves: C57BL/6 * MOL-NIS

 MP:0008878 abnormal DNA methylation during gametogenesis "any anomaly of the covalent transfer of a methyl group to C-5 of cytosine during gamete generation, when DNA methylation patterns are established" [GO:0043046]
Show

Allelic Composition: Mov10l1tm1.2Jw/Mov10l1tm1.2Jw
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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