ENSMUSG00000020721


Mus musculus

Features
Gene ID: ENSMUSG00000020721
  
Biological name :Helz
  
Synonyms : Helz / Probable helicase with zinc finger domain / Q6DFV5
  
Possible biological names infered from orthology : helicase with zinc finger / P42694
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: E1
Gene start: 107547930
Gene end: 107693826
  
Corresponding Affymetrix probe sets: 10382152 (MoGene1.0st)   1427469_at (Mouse Genome 430 2.0 Array)   1442293_at (Mouse Genome 430 2.0 Array)   1444942_at (Mouse Genome 430 2.0 Array)   1445453_at (Mouse Genome 430 2.0 Array)   1452443_s_at (Mouse Genome 430 2.0 Array)   1455059_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000097878
Ensembl peptide - ENSMUSP00000117498
Ensembl peptide - ENSMUSP00000102357
Ensembl peptide - ENSMUSP00000074533
NCBI entrez gene - 78455     See in Manteia.
MGI - MGI:1925705
RefSeq - XM_006534504
RefSeq - XM_006534505
RefSeq - XM_006534506
RefSeq - XM_006534507
RefSeq - NM_198298
RefSeq Peptide - NP_938040
swissprot - Q6DFV5
swissprot - A2AAU3
swissprot - A0A0R4J0Y3
swissprot - A2AAU5
Ensembl - ENSMUSG00000020721
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 helzENSDARG00000030560Danio rerio
 HELZENSGALG00000027152Gallus gallus
 HELZENSG00000198265Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Helz2 / E9QAM5 / Helicase with zinc finger domain 2 / Q9BYK8* / helicase with zinc finger 2*ENSMUSG0000002758025
Mov10 / P23249 / Putative helicase MOV-10 / Q9HCE1* / Mov10 RISC complex RNA helicase*ENSMUSG0000000222711
Mov10l1 / Mov10 RISC complex RNA helicase like 1 / Q9BXT6*ENSMUSG0000001536511
Upf1 / Q9EPU0 / UPF1 regulator of nonsense transcripts homolog (yeast) / Q92900* / UPF1, RNA helicase and ATPase*ENSMUSG0000005830110


Protein motifs (from Interpro)
Interpro ID Name
 IPR000571  Zinc finger, CCCH-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036855  Zinc finger, CCCH-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cst10tm1Hkaw/Cst10tm1Hkaw,Enpp1ttw/Enpp1ttw
Genetic Background: involves: C57BL/6 * ICR

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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