ENSMUSG00000002227


Mus musculus

Features
Gene ID: ENSMUSG00000002227
  
Biological name :Mov10
  
Synonyms : Mov10 / P23249 / Putative helicase MOV-10
  
Possible biological names infered from orthology : Mov10 RISC complex RNA helicase / Q9HCE1
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F2.2
Gene start: 104794836
Gene end: 104818563
  
Corresponding Affymetrix probe sets: 10500911 (MoGene1.0st)   1416380_at (Mouse Genome 430 2.0 Array)   1447376_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000002297
Ensembl peptide - ENSMUSP00000128246
Ensembl peptide - ENSMUSP00000126897
Ensembl peptide - ENSMUSP00000120486
Ensembl peptide - ENSMUSP00000102387
Ensembl peptide - ENSMUSP00000102386
NCBI entrez gene - 17454     See in Manteia.
MGI - MGI:97054
RefSeq - XM_006501101
RefSeq - NM_001163440
RefSeq - NM_001163441
RefSeq - NM_008619
RefSeq - XM_006501100
RefSeq Peptide - NP_032645
RefSeq Peptide - NP_001156912
RefSeq Peptide - NP_001156913
swissprot - D3YVL0
swissprot - D3Z3E8
swissprot - D3YYR1
swissprot - D3YVL1
swissprot - P23249
swissprot - E9PW39
Ensembl - ENSMUSG00000002227
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mov10aENSDARG00000015829Danio rerio
 Q1LXK4ENSDARG00000061177Danio rerio
 Q1LXK5ENSDARG00000056065Danio rerio
 MOV10ENSGALG00000001558Gallus gallus
 MOV10ENSG00000155363Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mov10l1 / Mov10 RISC complex RNA helicase like 1 / Q9BXT6*ENSMUSG0000001536530
Helz / Q6DFV5 / Probable helicase with zinc finger domain / P42694* / helicase with zinc finger*ENSMUSG0000002072119
Upf1 / Q9EPU0 / UPF1 regulator of nonsense transcripts homolog (yeast) / Q92900* / UPF1, RNA helicase and ATPase*ENSMUSG0000005830117
Helz2 / E9QAM5 / Helicase with zinc finger domain 2 / Q9BYK8* / helicase with zinc finger 2*ENSMUSG0000002758017


Protein motifs (from Interpro)
Interpro ID Name
 IPR026122  Putative helicase MOV-10
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0035195 gene silencing by miRNA IEA
 biological_processGO:0035279 mRNA cleavage involved in gene silencing by miRNA IEA
 cellular_componentGO:0000932 P-body IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001363 increased anxiety-related response "when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]
Show

Allelic Composition: Sucla2Gt(IST10208H1)Tigm/Sucla2+,Suclg2Gt(Ayu21-KBW131)Imeg/Suclg2+
Genetic Background: involves: 129S/SvEv * C57BL/6 * C57BL/6N

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Sucla2Gt(IST10208H1)Tigm/Sucla2+,Suclg2Gt(Ayu21-KBW131)Imeg/Suclg2+
Genetic Background: involves: 129S/SvEv * C57BL/6 * C57BL/6N

 MP:0008143 abnormal dendrite morphology "any structural anomaly of the highly branched tree-like process of a neuron that serves as a receptive field and conducts impulses toward the cell body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sucla2Gt(IST10208H1)Tigm/Sucla2+,Suclg2Gt(Ayu21-KBW131)Imeg/Suclg2+
Genetic Background: involves: 129S/SvEv * C57BL/6 * C57BL/6N

 MP:0011092 complete embryonic lethality "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Sucla2Gt(IST10208H1)Tigm/Sucla2+,Suclg2Gt(Ayu21-KBW131)Imeg/Suclg2+
Genetic Background: involves: 129S/SvEv * C57BL/6 * C57BL/6N

 MP:0013292 embryonic lethality prior to organogenesis "death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]
Show

Allelic Composition: Sucla2Gt(IST10208H1)Tigm/Sucla2+,Suclg2Gt(Ayu21-KBW131)Imeg/Suclg2+
Genetic Background: involves: 129S/SvEv * C57BL/6 * C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000041530 Ago1 / Q8CJG1 / Protein argonaute-1 / Q9UL18* / argonaute 1, RISC catalytic component*  / complex
 ENSMUSG00000028842 Ago3 / Q8CJF9 / Protein argonaute-3 / Q9H9G7* / argonaute 3, RISC catalytic component*  / complex
 ENSMUSG00000036698 Ago2 / Q8CJG0 / Protein argonaute-2 / Q9UKV8* / argonaute 2, RISC catalytic component*  / complex
 ENSMUSG00000042500 Ago4 / Q8CJF8 / Protein argonaute-4 / Q9HCK5* / argonaute 4, RISC catalytic component*  / complex
 ENSMUSG00000025571 Tnrc6c / trinucleotide repeat containing 6C / Q9HCJ0*  / complex
 ENSMUSG00000047888 Q8BKI2 / Tnrc6b / trinucleotide repeat containing 6b / Q9UPQ9*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr