ENSMUSG00000016534


Mus musculus

Features
Gene ID: ENSMUSG00000016534
  
Biological name :Lamp2
  
Synonyms : Lamp2 / Lysosome-associated membrane glycoprotein 2 / P17047
  
Possible biological names infered from orthology : lysosomal associated membrane protein 2 / P13473
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: A3.3
Gene start: 38401357
Gene end: 38456454
  
Corresponding Affymetrix probe sets: 10604187 (MoGene1.0st)   1416343_a_at (Mouse Genome 430 2.0 Array)   1416344_at (Mouse Genome 430 2.0 Array)   1428094_at (Mouse Genome 430 2.0 Array)   1434503_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000016678
Ensembl peptide - ENSMUSP00000052283
Ensembl peptide - ENSMUSP00000074448
NCBI entrez gene - 16784     See in Manteia.
MGI - MGI:96748
RefSeq - NM_001290485
RefSeq - NM_001017959
RefSeq - NM_010685
RefSeq Peptide - NP_001017959
RefSeq Peptide - NP_001277414
RefSeq Peptide - NP_034815
swissprot - P17047
swissprot - Q8C5K0
Ensembl - ENSMUSG00000016534
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lamp2ENSDARG00000014914Danio rerio
 LAMP2ENSGALG00000008572Gallus gallus
 LAMP2ENSG00000005893Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lamp1 / P11438 / Lysosome-associated membrane glycoprotein 1 / P11279* / lysosomal associated membrane protein 1*ENSMUSG0000003144734
Cd68 / P31996 / Macrosialin / P34810* / CD68 molecule*ENSMUSG0000001877419
Lamp3 / Q7TST5 / Lysosome-associated membrane glycoprotein 3 / Q9UQV4* / lysosomal associated membrane protein 3*ENSMUSG0000004124717


Protein motifs (from Interpro)
Interpro ID Name
 IPR002000  Lysosome-associated membrane glycoprotein
 IPR018134  Lysosome-associated membrane glycoprotein, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006605 protein targeting IMP
 biological_processGO:0006914 autophagy IMP
 biological_processGO:0009267 cellular response to starvation IMP
 biological_processGO:0031647 regulation of protein stability ISO
 biological_processGO:0032463 negative regulation of protein homooligomerization ISO
 biological_processGO:0046716 muscle cell cellular homeostasis IMP
 biological_processGO:0050821 protein stabilization IMP
 biological_processGO:0061684 chaperone-mediated autophagy IGI
 biological_processGO:0061740 protein targeting to lysosome involved in chaperone-mediated autophagy IMP
 biological_processGO:0097352 autophagosome maturation IMP
 biological_processGO:1905146 lysosomal protein catabolic process ISO
 cellular_componentGO:0000421 autophagosome membrane IEA
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005764 lysosome ISO
 cellular_componentGO:0005765 lysosomal membrane ISO
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005770 late endosome ISO
 cellular_componentGO:0005802 trans-Golgi network ISO
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030670 phagocytic vesicle membrane IMP
 cellular_componentGO:0031088 platelet dense granule membrane ISO
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031902 late endosome membrane ISO
 cellular_componentGO:0044754 autolysosome ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 cellular_componentGO:0061742 chaperone-mediated autophagy translocation complex ISO
 cellular_componentGO:0070062 extracellular exosome ISO
 cellular_componentGO:0097637 integral component of autophagosome membrane IDA
 cellular_componentGO:1990836 lysosomal matrix ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0019904 protein domain specific binding IPI


Pathways (from Reactome)
Pathway description
Platelet degranulation
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000088 short mandible "reduced length of the lower bony framework of the mouth where the inferior teeth are held" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

Allelic Composition: Lamp1tm1Psa/Lamp1tm1Psa,Lamp2tm1Psa/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000097 short maxilla "reduced length of the upper jaw bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53370]
Show

Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

Allelic Composition: Lamp1tm1Psa/Lamp1tm1Psa,Lamp2tm1Psa/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000428 abnormal craniofacial morphology "anomalous structure or development of the face and/or cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

Allelic Composition: Lamp1tm1Psa/Lamp1tm1Psa,Lamp2tm1Psa/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000435 shortened head "reduced anterior-posterior length of the head" [J:42035]
Show

Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

Allelic Composition: Lamp1tm1Psa/Lamp1tm1Psa,Lamp2tm1Psa/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000454 abnormal jaw morphology "malformation of the bony framework of the mouth where the teeth are held" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

Allelic Composition: Lamp1tm1Psa/Lamp1tm1Psa,Lamp2tm1Psa/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000599 enlarged liver "larger than average size of the liver" [J:65146]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0000603 pale liver "liver lacking normal coloration, often refers to bloodless condition" [J:18048]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0000609 abnormal liver physiology "aberrant function of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0000703 abnormal thymus morphology "anomalous structure or development of the primary lymphoid organ; required for immune system development" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55400]
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Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,Amhr2tm1Bhr/Amhr2tm1Bhr
Genetic Background: Not Specified

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,Amhr2tm1Bhr/Amhr2tm1Bhr
Genetic Background: Not Specified

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0001263 weight loss "progressive reduction of body weight below normal average for age" [J:45400]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0001284 absent vibrissae "missing whiskers" [J:18378]
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Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

Allelic Composition: Lamp1tm1Psa/Lamp1tm1Psa,Lamp2tm1Psa/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,Amhr2tm1Bhr/Amhr2tm1Bhr
Genetic Background: Not Specified

 MP:0002078 abnormal glucose homeostasis "anomaly in the state of equilibrium or processing in the body with respect to glucose in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Hap1tm2Xjl/Hap1tm2Xjl,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129 * C57BL/6 * CBA

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,Amhr2tm1Bhr/Amhr2tm1Bhr
Genetic Background: Not Specified

 MP:0002118 abnormal lipid homeostasis "anomaly in the state of equilibrium in the body with respect to lipids in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0002628 fatty liver "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0002639 micrognathia "abnormally reduced size of the jaws, especially of the mandible" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

Allelic Composition: Lamp1tm1Psa/Lamp1tm1Psa,Lamp2tm1Psa/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002833 increased heart weight "greater than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,Amhr2tm1Bhr/Amhr2tm1Bhr
Genetic Background: Not Specified

 MP:0002941 increased circulating alanine transaminase level "increased concentration in the blood of this enzyme, which transfers amino groups from l-alanine to 2 ketoglutarate, or the reverse (from l-glutamate to pyruvate); serum concentration is increased in viral hepatitis and myocardial infarction" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0002981 increased liver weight "a greater than average weight of the bile-secreting exocrine gland" [il:Ira Lu , Mouse Genome Informatics Curator]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0003325 decreased liver function "reduced normal function of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [ncbi:Matthew Mailman, NCBI request, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0003887 increased hepatocyte apoptosis "increase in the number of hepatocytes undergoing programmed cell death" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0003927 enhanced cellular glucose import "improved ability of a cell to take in glucose from the environment" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0004889 increased energy expenditure "increase in the number of calories used per unit time or decrease in weight gain for a given amount of food eaten" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0005058 abnormal lysosome morphology "anomalous structure of any of the cytoplasmic, membrane bound vesicles that contain a variety of hydrolases" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

Allelic Composition: Lamp1tm1Psa/Lamp1tm1Psa,Lamp2tm1Psa/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005140 decreased cardiac muscle contractility "inability or reduced ability of the heart muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,Amhr2tm1Bhr/Amhr2tm1Bhr
Genetic Background: Not Specified

 MP:0005289 increased oxygen consumption "greater than the normal rate at which oxygen enters the blood from alveolar gas; this is equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0005292 improved glucose tolerance "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0005311 abnormal circulating amino acid level "aberrant concentration in the blood of these organic compounds, which, when polymerized, form proteins" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:83263]
Show

Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,Amhr2tm1Bhr/Amhr2tm1Bhr
Genetic Background: Not Specified

 MP:0005455 increased weight gain "greater increase in body weight over existing weight when compared to the average increase in weight on the same diet, with equal energy (calorie) intake " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:42702]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0005459 decreased percent body fat "less fat, relative to the norm, as a percentage of total body weight" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0005584 abnormal enzyme/coenzyme activity "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,Amhr2tm1Bhr/Amhr2tm1Bhr
Genetic Background: Not Specified

 MP:0008260 abnormal autophagy "abnormal catabolic process involving the degradation of a cell s own components through the lysosomal machinery" [MGI:honda "Hiraoki Onda, Mouse Genome Informatics Curator"]
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Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0008475 intermingled spleen red and white pulp "no clear demarcation of the spleen red and white pulp tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,Amhr2tm1Bhr/Amhr2tm1Bhr
Genetic Background: Not Specified

 MP:0008963 increased carbon dioxide production "increase in the rate at which carbon dioxide leaves the blood and enters the alveolar gas" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0009122 decreased white fat cell lipid droplet size "reduction in the size of the single large lipid droplet or vacuole of white fat cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0009125 decreased brown fat cell lipid droplet size "reduction in the size of the multiple small droplets of triglycerides found in brown adipocytes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0009283 decreased gonadal fat pad weight "less than average weight of the encapsulated adipose tissue associated with the ovaries or testes" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0009355 increased liver triglyceride level "higher than normal concentration of triacylglycerols in the liver" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0009746 enhanced behavioral response to xenobiotic "increased sensitivity to a foreign compound capable of inducing the appearance of behavioral response, such as consumption preference, induced hyperactivity or stereotypic behavior, or reduced dosage threshold for the appearance of the behavioral response" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0010378 increased respiratory quotient "increase in the ratio of the volume of carbon dioxide released to oxygen consumed by a body tissue or an organism compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0010398 decreased liver glycogen level "less than the normal concentration of a readily converted carbohydrate reserve in liver" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

Allelic Composition: Lamp1tm1Psa/Lamp1tm1Psa,Lamp2tm1Psa/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0012138 decreased forebrain size "size reduction or truncation of the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions)" [GO:0048853]
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Allelic Composition: Kcnma1tm1Rwa/Kcnma1tm1Rwa
Genetic Background: FVB.129-Kcnma1tm1Rwa

Allelic Composition: Lamp1tm1Psa/Lamp1tm1Psa,Lamp2tm1Psa/Y
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0013278 decreased fasted circulating glucose level "reduction in the amount of glucose in the blood at some defined time point after eating compared to controls" [MGI:Armida_Di_Fenza]
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Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

 MP:0020103 decreased hepatic glucose production "decreased production of glucose in the liver" [GOC:NV]
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Allelic Composition: Lamp2tm1Amcu/Y,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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