ENSMUSG00000019865


Mus musculus

Features
Gene ID: ENSMUSG00000019865
  
Biological name :Nmbr
  
Synonyms : Neuromedin-B receptor / Nmbr / O54799
  
Possible biological names infered from orthology : P28336
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: A2
Gene start: 14705591
Gene end: 14770850
  
Corresponding Affymetrix probe sets: 10361818 (MoGene1.0st)   1422342_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020015
Ensembl peptide - ENSMUSP00000140754
Ensembl peptide - ENSMUSP00000140223
Ensembl peptide - ENSMUSP00000139695
Ensembl peptide - ENSMUSP00000139612
NCBI entrez gene - 18101     See in Manteia.
MGI - MGI:1100525
RefSeq - NM_008703
RefSeq Peptide - NP_032729
swissprot - A0A087WP36
swissprot - O54799
swissprot - A0A087WRS7
swissprot - Q0VEH1
swissprot - A0A087WQJ7
swissprot - A0A087WPA3
Ensembl - ENSMUSG00000019865
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nmbrENSDARG00000054152Danio rerio
 NMBRENSGALG00000013813Gallus gallus
 NMBRENSG00000135577Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Grpr / P21729 / Gastrin-releasing peptide receptor / P30550*ENSMUSG0000003136455
Brs3 / O54798 / Bombesin receptor subtype-3 / P32247*ENSMUSG0000003113046
Ednra / Q61614 / Endothelin-1 receptor / P25101* / endothelin receptor type A*ENSMUSG0000003161629
Ednrb / P48302 / Endothelin receptor type B / P24530*ENSMUSG0000002212229
Gpr37 / Q9QY42 / Prosaposin receptor GPR37 / O15354* / G protein-coupled receptor 37*ENSMUSG0000003990424
Q99JG2 / Gpr37l1 / G protein-coupled receptor 37-like 1 / O60883*ENSMUSG0000002642418


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001556  Bombesin receptor-like
 IPR001642  Neuromedin B receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0031989 bombesin receptor signaling pathway IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004946 bombesin receptor activity IEA
 molecular_functionGO:0008528 G-protein coupled peptide receptor activity IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001386 abnormal maternal nurturing "failure of mothers to tend offspring" [J:39801]
Show

Allelic Composition: Axin1Fu/Axin1Fu
Genetic Background: Not Specified

 MP:0001777 abnormal body temperature regulation "anomalous control of the body s heat" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Axin1Fu/Axin1Fu
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025723 Nmb / Q9CR53 / Neuromedin-B Neuromedin-B-32 Neuromedin-B / P08949* / neuromedin B*  / complex / reaction
 ENSMUSG00000024517 Grp / Q8R1I2 / Gastrin-releasing peptide Neuromedin-C / P07492* / gastrin releasing peptide*  / complex / reaction






 

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contact: otassy@igbmc.fr